How To Confirm The Causes Of Iron Deficiency Anemia In Young Women

Gastro-oesophageal reflux disease

All cases underwent gastroscopy with biopsies of stomach and duodenum, irrespective of tests results. Of the 115 patients, 45.2% of women were test-positive. The serological results were confirmed by gastroscopy in 100% of those with positive H. pylori antibodies, in 50% of those with positive tTG and in 81.5% of test-negative patients. Sensitivity and specificity were 84.8% and 100% for H. pylori infection, and 80% and 92.8% for tTG, respectively. The gastroscopy compliance rate of test-positive women was significantly increased in comparison with those test-negative (65.4% vs 42.8%; Fisher test P = 0.0239). This study showed that two simples and widely available tests, such as those for tissue transglutaminase IgA antibodies and anti-H. pylori IgG antibodies, were able to select women with IDA to submit for gastroscopy to identify IDA-related GI causes and to increase the compliance for the invasive procedure. Gastroscopy with biopsies confirmed in the vast majority of IDA women the presence of active H. pylori pangastritis, atrophic gastric body, or celiac disease as possible causes of IDA. Story Source: The above story is based on materials provided by World Journal of Gastroenterology . Note: Materials may be edited for content and length. Journal Reference: Vannella L, Gianni D, Lahner E, Amato A, Grossi E, Delle, Fave G, Annibale B. visit this site right here

1. Aetiology Around 10-20% of the adult population has symptoms of GORD at some stage of their lives. GORD is two to three times more common in men than in women. Its prevalence increases with age. Obesity, smoking, pregnancy, family history, hiatus hernia and various medications (for example, tricyclic antidepressants, nitrates, calcium-channel blockers) are all associated with GORD. Certain foods can relax the lower oesophageal sphincter, including chocolate, coffee, alcohol and fatty meals. GORD can lead to oesophagitis, but it is not very common; only around 8% of patients with GORD have moderate or severe oesophagitis. Some patients have abnormalities in their lower oesophageal sphincter which leads to reflux of their gastric contents. 2. Presentation Common symptoms include heartburn, regurgitation and dysphagia. Atypical symptoms include chest pain, cough, hoarseness and bloating. Symptoms are classically worse when lying down or leaning forward, and improve with antacids. look at more info

Evaluation of patient satisfaction of an outpatient gastroscopy service in an Asian tertiary care hospital

As dissatisfaction towards appointment waiting time could have resulted in a proportion of patients transferring to another outpatient gastroscopy service, our figure could be an under-estimation of the true proportion of patients who were dissatisfied in this aspect. Waiting times for endoscopy appointment and on endoscopy day are problems not restricted to our center but appear to be major causes of unfavorable responses in other centers as well [ 18 - 21 ]. In this aspect, it is vital that increasing patient load is matched by increasing allocation of resources to maintain a service that meets the expectations of not only patients but also of healthcare providers. Discomfort during procedure was recognized as the main cause of patient dissatisfaction in some studies [ 22 , 23 ]. Despite using proven measures to minimize discomfort during gastroscopy, including pharyngeal anesthesia and conscious sedation [ 7 - 9 , 24 ], nearly a quarter of our patients were not satisfied. We found that patients who were only minimally sedated were more likely to give unfavorable response for comfort during procedure (data not shown). In this aspect, routine use of OAASS as an objective measure of adequate (moderate) sedation prior to commencing the procedure may be of benefit. Besides sedation, other factors such as the diameter of the endoscope [ 25 ] and level of experience of the endoscopist [ 23 ] may affect the level of comfort during the procedure. However, our study was not designed to look into these factors. Besides waiting times and discomfort during procedure, other factors have yielded unfavorable responses from our patients. However, utilizing the principle of vital few and trivial many [ 26 ], we identified that waiting times and discomfort during procedure constituted to nearly 90% of the problems faced by our patients. By focusing on improvement in these aspects, there is great likelihood of substantially reducing the problem rate among patients attending our outpatient gastroscopy service. go to this web-site