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MEP amplitude and stimulation intensity did not differ significantly from that of Experiment 1. ANOVA for the 2 and 1?mA cathodal stimulation conditions revealed a significant main effect of tDCS (F1?=?23.691, P? http://www.selleckchem.com/products/Adrucil(Fluorouracil).html of the I�CO curve slope can be observed for the 1?mA condition (Fig. 4). MEP amplitudes were 1.91?��?1.33 and 2.73?��?1.83?mV before stimulation and 1.55?��?0.77 and 2.32?��?1.27?mV after stimulation at intensities of 130 and 150% of RMT, respectively. Intracortical inhibition and facilitation ANOVA showed a significant effect of ISI (F4?=?9.853, P? http://www.selleck.cn/products/Nutlin-3.html by the post hoc Student's t tests (P? http://www.selleckchem.com/products/GDC-0980-RG7422.html Active motor threshold Baseline AMT values in this experiment did not differ significantly from the respective values of Experiment 1. AMT was 32.1?��?9.4% of maximum stimulator output. The ANOVA results were not significant. Single-pulse MEPs (1?mV) The average baseline MEP value was 0.93?��?0.03?mV obtained by 51.6?��?12.7% of maximum stimulator output. MEP amplitude and stimulation intensity did not differ significantly from that of Experiment 1. ANOVA did not reveal significant main effect of Time (F3?=?0.142, P?=?0.93) (Fig.?2C). Intracortical inhibition and facilitation ANOVA showed a significant effect of ISI (F4?=?3.225, P?=?0.027) but no significant interaction between Time and ISI (Fig.?3D).