Curcumin Efficient Against Colorectal Cancer

Study: Curcumin Is King Against Colon Cancer

The study carried out by UTMB researchers is entitled 'Curcumin inhibits neurotensin-mediated interleukin-8 production and migration of HCT116 human colon cancer cells'. The team stated they hope that further studies on the idea of the current research will develop new strategies of fighting against colorectal cancer, by using curcumin to inhibit the production of the neurotensin hormone. Mark Evers, senior author of the study and director of UTMB's Sealy Center for Cancer Cell Biology pointed out: "Our findings suggest that curcumin may be useful for colon cancer treatment, as well as potential colon cancer suppression, in cells that respond to this gastrointestinal hormone, neurotensin. About a third of all colorectal cancer cells have the receptor for neurotensin." He also explained: "We found that in colon cancer cells, neurotensin increases not just the rate of growth but also other critical things, including cell migration and metastasis. The fact that all that can be turned off by this natural product, curcumin, was really remarkable." Curcumin is the yellow pigment found in the curry spice turmeric. Turmeric is commonly known as one of the cheapest spices, that has been used since antiquity as a condiment and also as dye. Originating in South East Asia, the turmeric contains curcuminoids that are the most beneficial ingredients of this plant. Read more..

Curcumin Dosage & Cancer

Thorpe Tagged With: colon cancer , Colon Cancer health , Curcumin , Curcumin benefits , Curcumin colon cancer The second leading cause of cancer-related death in America, colon cancer, is projected to take over 50,000 lives in 2013, just in the US. The steep death toll can be prevented, however, because the causes of colon cancer are preventable and are no coincidence. Cancer of the colon is based on risk factors acquired through lifestyle decisions. These risk factors do not include stereotypical medical excuses like family genetics and being over 50. Stereotypical colon cancer risk factors debunked People of the same family may harbor similar genes, but more importantly, they may pass on the same mindsets. Similar negative gene expression may actually come from families who tend to practice and teach the same philosophies about thinking, eating and medicating. In fact, gene expression can be completely altered and changed in the face of cancer when a new mindset and eating approach is undertaken. Read more..

Dose Researchers have not conducted sufficient evidence on the anti-cancer properties of curcumin to determine the most effective dose. A wide range of doses have been tested in humans, ranging from 0.5 g per day up to 12 g per day, reports the Linus Pauling Institute at Oregon State University. The available evidence indicates that doses of at least 3.6 to 4 g per day are necessary in order for curcumin to accumulate to detectable levels in the blood. You Might Also Like Turmeric & Curcumin for Maximum Dose Curcumin is classified as "Generally Recognized as Safe", or GRAS, by the U.S. Food and Drug Administration. Taking large doses of curcumin, up to 12 g per day, does not appear to increase the risk of severe adverse reactions, explains the Linus Pauling Institute at Oregon State University. Due to this lack of toxicity, the Institute of Medicine has not set a tolerable upper intake level of curcumin. Read more..