Celiac Disease

Lock & Key Antibody Test Could Boost Celiac Disease Diagnosis

It is a hereditary autoimmune condition in which a person has a delayed allergic reaction to gluten (a protein that causes dough to be sticky) found in cereals, such as wheat, barley, and rye. This sensitivity damages the lining of the small intestine so that it can't absorb nutrients from food. Celiac disease affects approximately 0.5% to 1% of people in Canada. Recent research has revealed that, contrary to what was previously believed, celiac disease may be just as common in places like Africa, South America, and Asia. Causes of Celiac Disease The lining of a normal small intestine is covered with finger-like projections called villi. The villi are covered with tiny hair-like endings called microvilli, which trap and absorb nutrients from food. In celiac disease, the villi flatten out or disappear due to the allergic response to eating foods containing gluten. The villi lose their shape and their microvilli, resulting in the damage to the intestinal lining. Although it was once thought of as a condition that always started in childhood, it is now known that celiac disease can develop at any age in susceptible individuals. You are more susceptible if you have a family history of celiac disease, have type 1 diabetes, or if you have other autoimmune conditions such as thyroiditis. In older people, celiac disease can be triggered by an intestinal infection or some other intestinal condition. Symptoms and Complications of Celiac Disease A person with celiac disease isn't able to absorb the nutrients from food. This problem of malabsorption can cause vitamin and mineral deficiencies. Iron deficiency from malabsorption causes anemia, which is a reduction in red blood cells. This can lead to fatigue and tiredness. Symptoms of celiac disease can include serious diarrhea, bloating, and cramps. talks about it http://chealth.canoe.ca/condition_info_details.asp?disease_id=144

Celiac disease occurs when an individuals own immune system overreacts to gluten. The inflammatory response damages the delicate lining of the small intestine, where most nutrients are absorbed. #Celiac is autoimmune- gluten intake leads to erosion of the intestinal wall which causes nutrient malabsorption #nypnutrition #abcdrbchat Barnabas Health ACC (@StBarnACC) June 25, 2013 Who gets celiac disease? About 1 percent of the population has celiac disease, according to National Institutes of Health statistics. Certain genes place individuals at increased risk for celiac disease, but not everyone who has those genes will get the disease. And genes are only half the story: The disease only develops when someone who is genetically predisposed to celiac eats gluten. Women are more likely to suffer from celiac. So are people with type 1 diabetes, Down syndrome, Turner syndrome, autoimmune thyroid disease and Sjogrens syndrome. Its more common in Caucasians than otherethnicitiesand anyone with a close relative who has the disease. Both children and adults can be celiac. An unknown percentage of people may not have full-blown celiac but struggle with gluten sensitivities or gluten intolerance. bonuses http://abcnews.go.com/blogs/health/2013/06/27/digesting-the-facts-about-celiac-disease/

Digesting the Facts About Celiac Disease

His poems, essays and photographs have appeared in Antioch Review, Blue Mesa Review, CALIBAN, Hayden's Ferry Review, Huffington Post, the Mississippi Review, and Slate among others. He is a member of both the National Writers Union, the International Federation of Journalists, and covers San Francisco Health News for Examiner.com . Ads by Google: Celiac.com 01/01/2014 - By enabling researchers to link antibodies with certain diseases, a new method could help uncover and confirm environmental triggers for diseases such as celiac and Autism . The researchers have two goals, according to professor Patrick Daugherty, a researcher with the department of chemical engineering and the Center for BioEngineering at University of California, Santa Barbara. First, they want to create diagnostic tests for diseases for which there are currently no blood tests. Next, they want to figure out what causes the diseases. The process works by mining an individuals immunological memorya veritable catalog of the pathogens and antigens encountered by his or her immune system Every time we encounter a pathogen , our bodies mounts an immune response in the form of antibodies that are specific for given antigens; molecular , microbial , chemical, etc. Each time our bodies mount this response, they form memory cells that are activated by subsequent encounters with that specific antigen . Responses can vary, from minor reactions to serious autoimmune diseases in which the body turns against its own tissues and its immune system responds by destroying them, such as in the case of Type 1 diabetes and celiac disease. People with celiac disease, for example, will have certain antibodies in their blood that bind to specific peptides short chains of amino acids present in wheat, barley, and rye. These peptides are the gluten that trigger adverse reactions in certain people. In the same way that a lock is meant to take only one key, these antibodies will only attach to specific sequences of amino acids that make up the peptides. The researchers want to figure out which antibodies are linked to specific diseases. previous http://www.celiac.com/articles/23511/1/Lock-amp-Key-Antibody-Test-Could-Boost-Celiac-Disease-Diagnosis/Page1.html