I have been off of Methotrexate and Humira for the past few months because I had Mono. Last week I found out that the Mono was completely out of my blood so my rhuemy told me to start back on the Methotrexate. I took it on Saturday and have been sick ever since. I am contemplating staying off of the Methotrexate and Humira all together because I can't handle being sick and tired anymore. I already quit Prednisone and Plaquenil is next. I'm thinking that Ibuprofen and Vicodin should be fine. Any advice?
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