I have been on remeron and klonopin for years. a little over a month ago I went to the Dr. and told her that they don't seem to be working anymore, so she added risperdal to the list. I couldn't take it because it started affecting my hormones and I actually started producing breast milk. So she weaned me off of that and started me on topomax. I now feel even more depressed, sick on my stomach, I can't eat, and I'm not sleeping well. I don't know if I should give up so early (its only been a week) or not. Has anybody else been on topomax and had help from it? Or should I go ahead and call the Dr.?