I know xyrem has helped a lot of people.
That being said, it didn't help me. I felt like I was overdosing on hard drugs every night. I literally could not lift up my head 20 min after taking it. I may have just been having a bad reaction with other medicine I take.

I will say though that I felt refreshed after 4 hours. Unfortunately when I took it I only had 5 hours of time to sleep a night because of my commute to school :-(

i've only been taking it for about 10 days or so now, It makes me feel all trippy and drugged, but doesn't help me sleep really, like lately I've only been sleeping if i didn't sleep the night before..my dr. keeps upping my dose, but like you i get headaches from it too..i dont know..im trying to stick it out for a while, because i desprately need it to work...

In two days of taking the xyrem, it made me so sick, and i was not the same person they knew me at work. They said it was affecting me terribly, and it was. I was on edge all day, and was just sick to my stomach. I would rather not ever have my brain sleep, with the affects it caused me in two days. Yea, I'm not going to take it anymore. Two days was enough for me of feeling bad, I would rather just be tired. I have to much going on in my day to day life, and it felt like that was just slowing me down.

I have been taking Xyrem for a few months now and it has helped me with EDS, cataplexy, and sleeping at night. I believe it takes several weeks to feel the full benefits of the medicine, so be patient. I don't like the way it tastes, either, but if adding crystal light or something along those lines makes it easier to take, then I would do that. I don't remember getting a headache from taking it, however when I first started taking Provigil (I've been taking Provigil for a year now), I had very bad headaches along with anxiety which went away after a week or two, so I think that will eventually go away if you can put it up with it for a few weeks longer. Of course there are some nights that I toss and turn and can't go back to sleep, but I think that for the most part, Xyrem has helped me.

I have been using Xyrem for several months now and it is a true wonder drug. It does have some major side effect issues like severe nausea and vomiting in the morning, but once you get to a dose that works it really does work. I know it does not make sense to wake up half way through the night to take more and that still bugs me, but in the end it works out. Try not to fight it so much, I did at first, but once you learn the drug and what it can do for you, you WILL feel better. I use surgar free tropical kool-aid or grape and that really cuts the flavor down. If you make it up 2 hours before you take it the flavor will go away as well, just shake well! I also drink a glass of milk 30 minutes before I take it and when I wake in the morning. I know the directions say not to drink or eat anything 2 hours before but this will seriously help the stomach and you wont feel as drugged. This was suggested by my doc and it really does help!

I took gamma for 5yrs. or more ,thats what they called way back when now it's xyrem,took the xyrem thru a sleep study . i lost 100lbs,made me sick the first 4 months , after that iwas good to go cataplexy was almost obsolite , stopped because of insurance reasons. i cataplexy came back about a 1yr after istopped been that way ever since. and gained the wait back. supposed to be non-addictive.need calcium , potasium suppplemts if i remeber right . 95is when i stopped

2tired2ty: I am getting nervous about the Xyrem. It is starting not to work as well these days. I am at the max 4.5 bid and it is not lasting but a few hours. I did speak to my doc who said it can wear off after long usage, but I have only been on it for about 6 months. It works much better than any other drug and again is bothers me that it is already wearing off. has anyone had this happen? My doc just upped my Ritalin so that helps but I really like the sleep I get. Any thoughts???

GIVE ME SOME!!!! pok i am seriously going to see my cinsultant on 18th and beg for some.. i want to try it... provigil is not working at all. and the chlomipramine is having no effect on my cataplexy.. which is now very extreme... i will let you guys know if i get it! i hope it is available here in the uk??? it had better be!!!

I took xyrem for about 2 months and I had weight loss, panic attacks, and could not function. My doctor told me that I could take this drug for the rest of your life, but I could not see myself taking this forever.