I've been on Provigil for about 3 years. It seemed to really help for a while. Now, not so much. I did skip it one day last week accidentally though and slept most of the day, so I guess it makes more of a difference than I realized. I might try saving it for days when I need to get stuff done....I don't know, I'm tired.-Jen

for me none of the wake up pills worked for any length of time.including provigil.some worked for a week or two but that was it.
i have found with me if i'm not in an exacerbation and i feel the fatigue coming on,if i stop every thing and rest even for 30 minutes there is a huge difference.if i try to push through it i can be down for days

This was the problem I had with Provigil, it kept me awake for sure, but really did nothing for the fatigue. I walked around wide awake, but so tired I wanted to sleep, but couldn't. So needless to say, I did not continue taking it! Talk to your doc! Good luck! DD

HI MY NAME IS CINDY I TAKE 200MG EVERYDAY. IT IS A STIMULANT TO GIVE YOU ENERGY.
I HAVE HAD NO PROBLEM WITH IT.
I HAVE AARP RX DRUG COVERAGE ASSISTANT PAY THEY PAY FOR IT. IT IS A HIGH PRICED DRUG
BUT I CAN FEEL THE DIFFERENCE
WHEN I DO NOT TAKE IT. BUT EVERY MS CASE IS DIFFERENT.
I WILL TELL YOU SOMRTHING I TAKE SOME CAFIENE WHEN I REALLY WANT TO STAY AWAKE THAT I MIXING THAT IT IS LIKE I AM ON A MIXED DRINK I DO GET A CHARGE I AM FILYING HIGH. BUT I DO NOT TAKE IT
ALL THE TIME. I HAVE BEEN TAKING IT FOR A YEAR NOW.
I JUST THOUGHT I WOULD PASS THIS ALONG.

CINDY

An interesting fact about his drug - it will counteract some birth control pills!! AHHH! Imagine my surprise when the pharmasist called to tell me he just discoverd that about 3 weeks after I had been taking it!

I have been taking 100mg provigil for about 2 months. it has been very good for me. If I dont take it I would sleep all day and night.I am secondary progressive,it really does seem to get me vertical.

i thought provigil sucked when i tried it, but i found out something very interesting from a psychiatry buddy.
i have ADD and take Straterra. Stimulants for people with ADD or ADHD can have minimal stimulant affects and more of a calming affect. reverse reaction.
we think that when i take the provigil it has a similar affect as ADD meds. I drug rep told my friend that there is some convo in the drug industry about provigil being used in the future for ADD.
i haven't found any other ideas for the damn fatigue.

lisa

I would get checked out--you might be having a flare-up. I cannot understand. Provigil has been approved for airline pilots and shift workers. Also you may need to switch to another drug like ritalin then back again--

I started with 100mg of Provigil in May and then found myself dosing up to 200mg a month later. It kept me awake, but like dnjmn, I was wide awake and could not sleep. It also made me dizzy and anxious. I felt like I was falling all the time even when I was sitting comfortably. I felt like I was addicted to it. I got a little mean when I didn't have it. I decided to taper myself off of it at the end of August. Also, the pharmacy called me 2 months later to tell me that it may counteract the bc pills like GoAwayMS. I read about that when my neuro gave me samples in May and he said he never heard of a problem. Well....lets just say I don't want to find out 9 mos later that it was a problem. LOL My PT suggested time management. Taking three 10 min breaks a day. Take them when you are at your peak, not when you are crashing. This has been the hardest exercise she has given me. Trying to stop for 10 mins and do absolutely nothing. When I can accomplish this task, I do feel better. Take care.