My doctor also told me that there is not evidence it works. I go to an MS Clinic and they are in the process of doing research on LDN now. I would rather take the interferon that is proven to help then something that most MS doctors do not recommend. That is just my opinion.

Try your PCP. Now my Neurologist will prescribe it but 5 years ago, my PCP read some of the documents I printed off the internet and went to some of the sites I referred him to and prescribed it for me saying "well, it can't hurt you".

He also knew it wasn't a "rip-off" scheme.

I'd try your primary care doctor, it is really "out there" for a Neurologist to do it, while you primary care doc should be most concerned about weather it will hurt your or not.

Good-luck, Larry

It is intended to stop progression and improve fatigue. At such a low dose there is no harm to your body, contrary to other thoughts. it can be used with copaxone only.

I get lots of questions on LDN and MS
1) As Maria said (and Im not trying to play the cynical evidence based medicine doc but here goes) there are NO published clinical trial on LDN and MS
2) There WAS a recent intriguing trial on LDN showing some results in patients with Crohns.
3) We know that the use of low doses of naltrexone for MS enjoys a worldwide following amongst MS patients and that there is overwhelming anecdotal evidence, that in low doses naltrexone not only prevents relapses in MS but also reduces the progression of the disease....but we need some hard data (which cant be tough to do as it exists for crohns and other illnesses)
4) It is proposed that naltrexone acts by reducing apoptosis (basically dying)of oligodendrocytes.
5) The medical community (of which I am a part) needs to study LDN and MS and publish those results...when we do Ill let you know
Dr O.

i am sorry. i should have asked.
are there any bad side-effects to ldn?
tonytony10

VIvid dreams and leg stiffness are the only side effects and they are not bad.

Same thing happened with my Neuro! He said he may as well give me red pills to take because even though there are people who rave about it...it has no evidence to support it! I guess you just have to either trust in what your neuro says or go and see a GP, they can prescribe it too!

oh really?

So, ask him how he explains AUTISTIC CHILDREN being helped:

1. they don't know they're taking LDN, or could even pronounce it if they did

2. LDN is applied while they're SLEEPING, so they don't even know they're getting anything

3. it's applied transdermally so they're not even involved in the process

Can't be a placebo when it comes to chemical reactions in patients who aren't even aware they have a problem, much less medicine to try to help them.

Hey don't shoot the messenger!!! haha! Just relaying what the meuro said!

wasn't shooting, you, was giving you ammunition to shoot at HIM! :)

LDN helps me with fatigue. I don't know if it stops progression or anything else. It makes me FEEL BETTER. As stated by others--it does no harm. I've seen on this site that docs prescribe all kinds of heavy duty narcotic pain meds for some folks with MS. Does that make sense? They will prescribe addictive narcotics but not LDN? This sounds more like they get off on the power they have over you as a patient then that they working in their patients best interest. Once they tell you what there opionion is of LDN, and give you their advice, they should check their egos at the door and give you a script. :) just my opionion :)

ow about all the "anecdotal" evidence on the Internet. Plus it is cheap and as my PCP said "what have you got to lose".

Actually, I think you have a better chance of getting your PCP as opposed to a Neurologist to prescribe it as another Doctor won't be hung up on effectiveness for MS.

You might look up Its effectiveness for other Autoimmune diseases like Chrones Disease.

Refer you PCP to www.lowdosenaltrexone.org. Maybe he/she will also adopt the attitude of "well it can't hurt you" and for the money involved it certainly isn't a scam.

Good-luck.

Larry

This is such a useful thread.

I think I read somewhere that there are no published studies for the efficacy of Asprin but it is still used.

it can be used with copax? hmm...i think i might ask about this...