I finally convinced my Sister in law to ask her Dr. for LDN. She has scleroderma. He said no. I told her to find a Dr. on the website. She did and he is going to give her an aptt. on the phone on the 29th. I will keep everybody posted on the effects. She has got to ween off the Vicodin that she takes for pain. I have been trying to get her to take it for 5 yrs. Can't wait. Is there anyone out here who knows of LDN and Scleroderma?