I had my 5th IUI today and will have second day of IUI tomorrow. I was bummed when my RE office called me yesterday after my ultrasound and said I had 1 leading follicle. This is the second cycle I tried with letrozole instead of clomid. My RE recommended letrozole since it allowed for a better uterine lining and had less emotional effects. But, RE did mention there may not be as big of a response as with clomid. With the clomid cycles I always had 3 or 4 follicles. Last month with my first letrozole cycle I had 2 follicles and now this one only 1. I'm thinking why did I go through injections and hormones for the same result as if I did nothing? Ugh... Has anyone else had this same response/difference with using letrozole? I was taking 2.5 mg of letrozole,, maybe that wasn't enough?
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