Hi there, I am not sure about the antibody thing, but I do post on another site where there is a RE who gives advice (he is away until January). When ever someone posts something like what you have posted he advises to test for thyroid screen, clotting screen and NK cell anlaysis. Not sure what the last two are, but he always says that after a BFN. Have you had those things done? Good luck and I hope you get some answers.

I am not sure what kind of antibody test I had. I have Rh negative blood. 16 years ago I had a baby with my Rh positive boyfriend. Now- I was TTC for 7 months( we use frozen donor sperm) I got pregnant and it ended in m/c 6-7 weeks later. The donor was Rh positive. I was given a shot of rhogram (sp) We then tried again with the same donor. I felt pg but I was not late. I went to the OB who tested my HCG. Well I was again pg. She said it was a chemical pg b/c my antibody's would kill the pregnancy. The problem had to do with Rh factor. She also said that it was very likely that I had gotten pg those 7 months that we TTC. As soon as we switched to a Rh negative donor I became pg.(We tried and conceived the first month) That pg ended 23 weeks later with a stillborn but it had nothing to do with Rh. I know that most do not have the ability to turn in their husbands for a new one. But you can continually test your antibody level to make sure it is safe. If it gets into the unsafe range there is medicine to bring it back down. Usually this does not happen with the first pregnancy. Good luck- Sorry if I was not very clear feel free to message me if you have any questions.

I am so sorry this ended in a BFN. I am glad they could freeze some.
I don't have the answers to your questions, but it would be good to see the responses. If this cycle had ended in a BFN I was going to have them check other things. But since it ended before that point, I will have to wait.

Are you going to request more tests? Kyspier's response is interesting.

Hi there
the ANA is (+) in all autoimmune disorders so could signal autoimmune thyroid disease, antiphospholipid antibody syndrome, lupus, etc. I would get Thyroid peroxidase antibodies (TPO antibodies) which someone mentioned here because autoimmune thyroid disease is a well documented cause of increased pregnany loss....hang in there
Dr O.

Hello...

I'm so sorry to hear about your failed IVF, I can only imagine how sad and confused you feel when everything seemed to be perfect. I wanted to let you know that I have been tested for ANA and I am positive. My titer was 1:320 which is high but not enough for Lupus or any other type of autoimmune disorder. I'm in the 5% of the normal, seemingly healthy population with ANA. I have lost 4 pregnancies due to this disorder (or so my doctors believe that is why) but didn't know/test until after the 3rd loss. Once pregnant the protocol is one shot of Heparin/Lovenox in my stomach once a day. I did this this with my 4th pregnancy back in July 2007 but unfortunately it ended for another reason within 2 weeks of finding out we were expecting. We are 7 years and trying, I'm 36 years old and my husband is 38. I must add that the only reason I got pregnant the 4th time (it was 3 years since the last pregnancy) is because I had done one month of acupuncture and chinese herbs. We will do that again soon in 2008 when I'm mentally ready to try again. After 7 long years of heartache and disapointment I don't bounce back as quickly as I used to. I wish you the best for your next attempt, I will keep you in my thoughts and prayers. Positive thoughts will get you a long way...