For the last couple of years I've noticed my face is puffy. It's adding age and stress to my face. I was told that once my thyroid levels were at a somewhat normal level, this would taper off. Well I've slowly been upped to 125mcg of Synthroid, a bp med with diuretic, etc.. I noticed today my face is STILL quite puffy. Maybe more. What the heck? Will this ever leave?? I'm approximately 50-60 lbs thinner than I was when I started this nasty journey with my thyroid, five years ago. Granted, I'm 5 years older but the puffiness is driving me insane! Is this something that everyone battles with?