HPV Support Group

Human papillomavirus is a diverse group of DNA-based viruses that infect the skin and mucous membranes of humans. More than 100 different human papillomavirus (HPV) types have been characterized. Some HPV types cause benign skin warts, or papillomas, for which the virus family is named. HPVs associated with the development of such "common warts" are transmitted...

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CIN 1 and Negative HPV test

deleted_user
deleted_user
I have had repeat colposcopies and pap smears show LGSIL/CIN 1 for almost 2 years now, but the HPV DNA done at the 1 year mark was negative.

Can this be right? It is a mistake, right?

If it's not a mistake, how is this possible? My doctor said even she was confused.
deleted_user
deleted_user
After doing some reading up, it seems like this is not uncommon. The best explanation is that although your body is surpressing the HPV at this time, the mild dysplasia is taking a long time to clear.
You can discuss with your doctor various options including watching and waiting. You don't say how old you are, but if you are anywhere near menopause, this could also be one reason why the mild dysplasia is hanging around.
Unfortunately, the connection between HPV and cervical cancer is still new enough that there's just not enough information out there and even doctors sometimes don't have answers.
Christine1976
Christine1976
I just had my first pap 6mos after having a LEEP...I had the same result...still showed mild CIN1 but neg for HPV. I was told a couple of things...1) that the strain of HPV that the test tests for may not be the one I have. And 2)basically what wachit said. I still have two warts as well. Have had no new ones for 6 wks...just can't get rid of these!
deleted_user
deleted_user
Thanks for your replies! Well, I am only 24 years old, and no genital warts.

I did find some info about the Digene HPV DNA test (interpreting results). It sounds like positive/negative results are based on the concentration of the virus. So if you have a low concentration of the virus, it will come back negative.

I think I will ask for another HPV DNA test at the 2 year mark. I think that if it comes back negative, I would prefer the watching and watching to LEEP (because I want to have children).

If anyone else has any personal stories to share, please do. I feel pretty alone with this. Thanks!
Christine1976
Christine1976
That's good to know. Having a LEEP doesn't effect your fertility
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