You could try a Vitamin B complex for energy.
I use heat therapy (heating pads, a friends hot tub) and massage for knots (usually my mom). I know that driving irritates the muscles in my knees and shins. I at times switch legs to even things out.

dont forget your daily potassium for leg cramps, especially if you take meds that leach it from your body. You will probably also get an energy boost from cutting as much sugar from your diet as possible and increasing protien. Sugary and carb-loaded treats mess with insulin, and have a rebound effect that makes us crash soon after we eat them. If you snore or wake up alot at night, that really zaps your energy. Consider having a sleep study.

After 25 years of being sick, the thing that has helped my energy the most is amino acids like 5-HTP, GABA, L-glutamine and L-tyrosine. The reason they help is that they normalize the brain chemistry. I'm feeling normal since adding them for the first time since getting sick.

Here's a great article on the role of neurotransmitters in fibro. Amino acids are the building blocks of neurotransmitters:
http://www.drmurphreestore.com/newsletters_letters/arefmspatcrazy.html

I have a feeling the knots in your legs are myofascial trigger points, or knots in the muscles that refer pain elsewhere. I have them absolutely everywhere!!

The good news is that you can break them up [more or less] so they don't cause pain with trigger point massage. I use the book featured at triggerpointbook.com and can't recommend it highly enough. It's saved me untold suffering and having to be on pain meds. I use a two-headed percussion massager simply because I had it when I learned about TP massage. It works well as it glides easily over clothing and I can reach all areas of my body with it.

if you can...find a massage therapist that has researched FM...a good physical therapist as well....because exercise is IMPORTANT...and he/she will show you how to get restarted...and yes you basically have to start from the ground back up...we simply cannot do all that we used to...if you have any joints that tend to slip out of place a good chiro that is Knowledgeable in FM is also very beneficial...and conserving energy...you simply have to learn priorities...what NEEDS to be done first...resting BEFORE you become to fatigued...as once you are already fatigued the chances of you getting back up to finish a task is greatly diminished...learn to say ummm, No without Guilt [that is a tuffy}...and listen to WHAT ur body is telling you...stressful situations MUST be avoided when at all possible...not always possible {i get that}...if you have issues with meds {as I do} there is hope for some relief without the use of meds...also...get ur Vitamin levels checked...if you are deficient take supplements...I take B vitamins and D vitamins...both those were deficient even tho I get plenty of sun exposure...be patient...research...listen...and do NOT buy into "Miracle Cures"

i take alot of hot baths to help my legs and hips..hot showers for my shoulders and and me and my heating pad are on a first name basis..**hugs**

I will be honest, I take Provigil and Adderall. It helps me get through the day and work. I tried supplements, which I still take, and they don't work much for me.

Lolabell,

How effective have you found the meds? I also attending school fulltime but had to drop out cause ive been so tired that i would literally fall asleep driving to school (which is less than five miles away)

its sad its like im sick and tired of being sick and tired