I don't know of anyone who used it to get out of a cocaine addiction, but a reseach showed that it wasn't really effective.
It's still an experimental treatment.

"Cocaine addiction
A single 8-week double-blind study of modafinil for cocaine dependence produced inconclusive results. The number of cocaine-positive urine samples was significantly lower in the modafinil group as compared to the placebo group in the middle of the trial, but by the end of the 8 weeks the difference stopped being significant. Even before the treatment began, the modafinil group had lower cocaine consumption further confounding the results. As compared to placebo, modafinil did not reduce cocaine craving or self-reported cocaine use, and the physicians ratings were only insignificantly better.[33] Dan Umanoff, of the National Association for the Advancement and Advocacy of Addicts, criticized the authors of the study for leaving the negative results out of the discussion part and the abstract of the article.[34][35]"

Source:http://en.wikipedia.org/wiki/Modafinil

Where links lead:
33-http://www.nature.com/npp/journal/v30/n1/abs/1300600a.html
http://www.ncbi.nlm.nih.gov/pubmed/15525998
34-http://www.nature.com/npp/journal/v30/n12/abs/1300866a.html
http://www.ncbi.nlm.nih.gov/pubmed/16294193
35-http://www.nature.com/npp/journal/v30/n12/abs/1300867a.html

I wish It helps you!

this is interesting because my husband who is a cocaine addict, tried modafinal himself....maybe he was seeing if he could use that instead of cocaine..but needless to say it didnt work.

But he was self-medicating anyway, he didnt go to a dr. so it wasnt being prescribed in a controlled ennvironment. He ordered it off the internet.....so he was abusing it.

I just think it is just "switching addictions" maybe the modafinal isnt as harmful , but it is not getting the addict clean and sober.

what kind of dr. did you husband see?? was it an addiction specialist?? yo have to be careful too of dr.'s. my husband's so-called addiction specialist put him on suboxone but does not drug test him and so he can still use and get the soboxone. He also was supposed to follow-up with my husband on him being in therapy and he doesnt do that either. I dont trust these dr's somethimes they just are in it for the money.

YES. Modifinil eliminates the possiblity of someone getting high on Cocaine. It doesn't mean however, they won't choose another drug to get high on. the dosage is 2 200mg tablets every morning. Initial side effecs are headaches and inability to sleep, but these subside within 2 weeks. Modifinil, Modalert or Provingil work best on someone who has bi-polar with addiction.

what do u mean?? you cant get high on coke is you take medafinal??
i dont think so.....

its not a blocker like suboxone is an opiate blocker for opiates.

its just another way to "feel better" for the addict.

im wrong...sorry...look at this article:

Throughout the study, modafinil-treated patients gave fewer cocaine-positive urine samples than the placebo group. "More impressive, though, is the fact that more than twice as many modafinil patients as placebo patients (33 percent compared with 13 percent) were able to attain abstinence for 3 weeks or more," Dr. Dackis says. "Maintaining abstinence for a prolonged period during treatment is an important clinical threshold. Cocaine is a binge drug, and it is common in outpatient treatment for a patient to go 4 or 5 days without using, relapse, then have another clean week. The long continuous abstinence we saw with modafinil is a strong and encouraging signal that this medication can help patients avoid relapse during the critical first weeks of treatment." Both groups of patients attended the same average number of CBT sessions, he adds, further supporting the likelihood that modafinil was the factor accounting for reduced cocaine abuse in those who received it.

Modafinil, a medication currently used to treat narcolepsy, enhances levels of glutamate, a chemical that influences the activity of cells throughout the brain. Animal research has shown that repeated exposure to cocaine depletes glutamate levels in brain regions associated with development of dependence and addiction, and that increasing glutamate concentrations will block reinstatement of cocaine self-administration in ratsa model of relapse to drug abuse in humans (see "Brain Glutamate Concentrations Affect Cocaine Seeking," NIDA NOTES, Vol. 19, No. 3).

Modafinil's modulation of glutamate transmission may account for a striking effect reported by patients: "The mechanism for this isn't clear, but some patients receiving modafinil told us that if they did use cocaine it did not produce the irresistible urge to use more, which they had always felt before," Dr. Dackis says. "Some of the patients told me they had flushed cocaine away. In 25 years of treating addiction, no one ever told me they threw away cocaine."

"The body of research suggesting that modafinil is effective in treating cocaine addiction is growing," says Dr. Ivan Montoya of NIDA's Division of Pharmacotherapies and Medical Consequences of Drug Abuse. "Animal research supports the assumption that modafinil reverses the cocaine-induced neurochemical disruptions of glutamate and of dopamine-containing neurons in the brain's reward centers. Clinically, modafinil has effects that are opposite to the symptoms of cocaine withdrawal, which usually include oversleeping, depression, poor concentration, and craving."

Dr. Dackis and his colleagues are now planning the next test for modafinil: a multisite clinical trial that will include more than 650 participants. The study will evaluate modafinil's efficacy in doses of 200 mg and 400 mg per day in combination with CBT, and results may be available by mid-2006, Dr. Montoya says.

Source

* Dackis, C.A., et al. A double-blind, placebo-controlled trial of modafinil for cocaine dependence. Neuropsychopharmacology 30(1):205-211, 2005. [Abstract]



Volume 20, Number 3 (October 2005)


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some more info:

this is very interesting..i never heard of this...i think its still in the clinical trial phases though...i dont think my husband would go to a dr. and get it and go to therapy...they are saying it works best with a combination of therapy.

Hes on soboxone for opiates, then he'll go to modifinal for cocaine...whats would he then try next??? meth...??

if he doesnt get the additional help, like going to 12 step or therapy
he will never get better.


MODAFINIL (PROVIGIL)

What it does: reduces high from cocaine and also reduces cocaine cravings

How it works: unknown... but it does increase glutamate in the brain

Side effects: most common side effects are headache, back pain nausea, nervousness, insomnia and anxiety.

Availability: by prescription from physicians

Warning: it is a schedule 4 drug so there is some potential for addiction to it

Dackis CA, Kampman KM, Lynch KG, Pettinati HM,O'Brien CP. "A double blind, placebo controlled trial of modafinil for cocaine dependence." Neuropsychopharmacology. 30: 205-211, 2005.

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I took Provigil from http://4rxstore.com/ several years ago for my sleep disorder. Stopped because I thought I could deal without and was expensive. Three years later, I am on again. I need it. I have idiopathic hyper insomnia. It doesnt make me shaky or hyper and wears off in time to sleep at night. Helps me through the day and works well for me. I take 400 a day and other than occasional headaches at night, no problems at all. It is my lifesaver and worth the money!

Ann, it's an excellent treatment for your condition, I have a friend with the same thing and I've done alot of reading about it. I am so glad you found it - sleep disorders are the pits.