I had the same thing back in '95. A few years later, I was tested & found to have a protein S & C deficiency. Both protein C and protein S are anti-clotting factors & you can have one or the other or both. When one of these proteins is low, the person is at increased risk of developing, blood clots which usually develop in the veins of the legs, but may occur at other sites. It is rare and many doctors have never heard of it. It's hereditary & does not skip a generation. The unfortunate thing is, you can't be tested for it if you are on warfarin/coumadin. (I took myself off coumadin - definitely would NOT recommend that to anyone else! - & was able to be tested for it 2 years later when I specifically asked for the test.) Protein S &/or C deficiency could be one of the possible causes for your unexplained DVTs.

I also had an unexplained DVT. I was not on BC pills, I don't fly and I have no family history. My initial labwork has not shown a blood clotting disorder. I do have two other test coming up in a few weeks (I had to be off Coumadin for these tests). I wish I could remember the name of these tests, but my hematologist said the disorders they were testing for were very rare.

~Dani

my 20 year old son has been in & out of hospital 3x in 1 year for this.
after ruling out all the obvious & most common CAUSES,
they now think it is a genetic abnormality of some sort.
testing for Factor V Leiden, Lab 21 test, F5 gene mutation
MTHFR
C6677T
i really don't understand it but look up these things on the web,
it has been informative & also have found lots of natural things to do for his DVT

I've had my genetic testing done and they were all ok. So the only thing I can put mine down to is pregnancy. Which is a risk factor on it's own.

I was diagnosed with DVT in right leg first of Aug. this year. I was found to have two clots in right leg. One the length of leg. I had similiar symptoms in left leg one year earlier but never was diagnosed. My mom might haved had genetic factor for clotting(after death found out causes of multiple mystery symptoms where most likely from clotting besides PEs at end). Her Dad also(At 53 massive PE). I had no reason to clot other than genetic. They cant do all testing on me do to being on blood thinners right now and probably the rest of my life. My Hemetoligist says that about half of the genetic clotting disorders havent been named yet. Just because they haven't matched it to a specific name doesnt mean it isnt genetic. With possible family history and multiple clots with no reason he says it is most likely gentic.