i was on prednisone and asacol 4 years ago and all it did was make me fat and miserable, then i was on pentasa for the last two and ended up having surgery two months ago. now i am still on the pentasa and also imuran with the posibility of remicade in the future, the imuran is giving me headaches, diahrehha (if its not the chron's back already, and very very achey knees)....i feel for ya!

I'm on both meds and I try not to worry about the risks of cancer. My GI said that he wants to take me off of the Imuran in 6-9 months because the risk of cancer increases if you take both medicines together for over a year.

I was diagnosed with Crohn's in '02 and started receiving Remicade treatments in early '03. Remiade worked wonders for me for 5 1/2 years. Unfortunately, a few months ago, I developed drug-incuded Lupus and vasculitis from the Remicade and had to stop getting the treatments. I'm slowly getting better, and I believe (hope) the drug-induced Lupus will be gone shortly. Even though Remicade caused me to have problems in the long run, I wouldn't have traded it for anything in the world. It gave me my life back for 5+ years!! If your doctor is recommending it, go for it. (Prior to Remicade I had been on Pentasa, Asacol & Prednisone....none of them worked for me.) Good luck to you!