End Stage Liver Disease and have had low platelets for about 4 going on 5 years now (same time I was Dx with Chronic Hep C/Cirrhosis). Started out around 90, 000 and now they stay at around 40,000. When I took the treatment they went down to 20,000. So my spleen has been eating up my platelets. Ok I need to know if anyone with Cirrhosis had had their Spleen removed. I had a Ultrasound done on Friday and my spleen is now at 19 cm. It was my understanding that it wouldn't be wise to take it out with the liver not functioning right. Could it burst??