Hi: I am on Gleevec, not Sprycel. My counts are holding at 3.5 most of the time. Sometimes they go up to 4. Its my red count and Hemoglobin, and they are always holding in the same range. Low but holding. They usually watch the platelets in case of a transfusion.
Do not worry. Your doctor will keep on top of the situation, and know if a transfusion is needed.
I have been doing this since 1998, so hope that makes you feel better.

4000 is perfect, but it would NOT be uncommon for the counts to go lower, many CML patients taking a TKI drug live with below "normal" blood counts. They would have to dip quite low before intervention is needed. My counts made it down to about 3700 and then bounced back up a little above 4000.

Sounds like he is doing great! Amazing that after a couple of weeks, something that was so out of control could be back to normal just by taking one pill a day. Amazing times we live in, we are very fortunate (despite the whole cancer thing :) )

Hope he continues to do well.

I am finally feeling a little at ease with my husband's CML. I asked the doctor when he would be in remission. The doctor replied that they will check his bloodwork after he's been on the CML meds for atleast 3 months. Guess it takes that long for the meds to stabilize and really get things under control. Thank you TKI guy for really explaining what CML is. I've read much about this but your explanation was so helpful. My husband is feeling better for the most part. The only side effect that bothers him yet is the heart palpitations and feeling breathless at times.

Dear Raineie, My husband is also on Sprycel for over a year now his counts have stabalized his #'s on there own with the medication and he has not had to have any transfusions yet. Thank God. I can see how that would be kinda scary, it's a scary thought for me. So far so good on the counts for him.