When my man first began on meds they Rx'd Depakote 250mg Twice a day...this was then upped to 500mg twice a day. HOWEVEr, when they upped him, they switched it to Depakote ER twice a day...shouldnt he be taking the 1000mg at one time since it is ER...anyone else taking multiple doses while on Depakote ER. I am thinking tat if he only had to take it once a day he could be alittle more consistant
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