
Amputees Support Group
Amputation is the removal of a body extremity by trauma or surgery. Many have undergone amputation or have been living with a missing limb since birth. In either case, life as an amputee can be challenging. This is the place to find others going through the same experiences as an amputee. Share your thoughts, troubles, and solutions with the community.

deleted_user
After 30 years of doing battle with phantom pain mostly at night/trying to sleep, I lucked out with a new Provessor of Medicine/Doctor in our tiny mountain community. We hit it off well and he seemed sincere when he said "give me two weeks to do some research" and he would get back to me. 10 days later he called and asked me to come in. phanton pain originates in the brain. Victims of shingles often have severe or moderate pain that also originates in the brain. There is a new drug (non-narcotic) called Lyrica that was developed for shingles pain and seizure. We started at a moderate dose 75mg per day. But he gave me an OK to try taking it at different times and to go up to 300 mg per day. It took a week to start working but at 300 mg it worked. I now take it 2 hours prior to bedtime and with a few exceptions, the pain vanishes by bed time. My is not a PAIN but a tingling sensation that drives you nuts when you are trying to sleep. When I over do it, walk to much, spend too many hours on my feet, the phantom sensation is stronger and I now have his OK to go up to 450 MG as needed. The max daily dose is about 800 mg but this is for severe shingles victims. Lyrica is not cheap but my insurance company picks up 90% of the cost. If you have an amputee support group, please share this info with them. Only side affect is that it does make you sleepy so I never drive after taking Lyrica - I just look forward to a good nights sleep!
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Pregabalin (INN) (IPA: [prgbln]) is an anticonvulsant drug used for neuropathic pain, as an adjunct therapy for partial seizures, and in generalized anxiety disorder. It was designed as a more potent successor to gabapentin. Pregabalin is marketed by Pfizer under the trade name Lyrica.
Recent studies have shown that pregabalin is effective at treating chronic pain in disorders such as fibromyalgia[1] and spinal cord injury[2]
It is considered to have a dependence liability if misused, and is classified as a Schedule V drug in the U.S.[3]
History
Pregabalin was initially developed by biochemist Richard Silverman at Northwestern University in the United States. The drug was approved in the European Union in 2004. Pregabalin received U.S. Food and Drug Administration (FDA) approval for use in treating epilepsy, diabetic neuropathy pain and post-herpetic neuralgia pain in June 2005, and appeared on the U.S. market in fall 2005.
Pharmacology
Like gabapentin, pregabalin binds to the 2 subunit of the voltage-dependent calcium channel in the central nervous system. However, the exact mechanism of action is unknown.
Clinical use
Indications
Pregabalin is indicated for:
Treatment of neuropathic pain in adults
Adjunctive therapy in adults with partial seizures with or without secondary generalization
Fibromyalgia pain. The FDA has approved Pregabalin as an indicated use on June 21, 2007[4].
In the European Union, it has also been approved for the treatment of generalized anxiety disorder (GAD).[5]
Adverse effects
Adverse drug reactions associated with the use of pregabalin include:[6][7]
Very common (>10% of patients): dizziness, drowsiness
Common (110% of patients): visual disturbance (including blurred vision, diplopia), ataxia, dysarthria, tremor, lethargy, memory impairment, euphoria, weight gain, constipation, dry mouth, peripheral edema, loss or decrease of libido, erectile dysfunction
Infrequent (0.11% of patients): depression, confusion, agitation, hallucinations, myoclonus, hypoaesthesia, hyperaesthesia, tachycardia, excessive salivation, sweating, flushing, rash, muscle cramp, myalgia, arthralgia, urinary incontinence, dysuria, thrombocytopenia, Kidney calculus
Rare (
Glad to hear you have found relief from your pain.
I have been on Lyrica since February. It only takes the edge off of my phantom pain. Norco (a narcotic mixutre of codine and tyleonol), is the only thing that really works for my pain. These drugs cause me to sleep an excessive amout...and I'm told can become addictive.
By the way, gabapentin, mentioned in Tigertatt's post is also called nerontin...a drug which is prescribed for phantom pain as well. It has been around a lot longer than Lyrica and has also proven to be useful.
Lorri
SkiKing
phantom pain does it usually right away or do i still have this coming. maybe i have been lucky but i have had very little pain from the word go pain pills for 3 or 4 days after operation,but i did have bad pain and many operation over the past 30 years\.. ty much Joe
There is a lot to be learned in this kind of informal exchange.
SkiKing