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Sodium oxybate is used to reduce the number of cataplexy (weak or paralyzed muscles) attacks in people with narcolepsy. This medicine is available only with your healthcare professional's prescription, and you can only get it from one central pharmacy. Before you use sodium oxybate your healthcare professional shoul... continue

Treatment Success Rate

Top 5 Communities
Condition Members Success
Chronic Pain
Bipolar Disorder
Overall, 84% (214 Members) find Xyrem helpful

Xyrem Reviews

Show: for
Working / Worked
Very strong drug but I am sleeping regularly and my episodes are brief and infrequent now. It's working. Not sure of any specific side effects yet.
Working / Worked
Taken it for a month. Rough at first but wow! Life changing once I added nuvigil
Working / Worked
Helps me get a deeper sleep at night
Working / Worked
Worked very well for cataplexy but scary, to impossible to function, if, for example need to get up for child, use restroom.
Working / Worked
In the beginning I hardly ever had to take my "stay awake meds". I definitely wake up a lot easier still.
Working / Worked
At full dose over a year
Working / Worked
Only been taking for three weeks, has been life changing. A few side effects especially since I don't use salt anyway.
Working / Worked
I was ecstatic when I started it and was able to get 6 hrs! of sleep. Into the third titrating dose I began to have strange s/e's like blurry and double vision,crazy thoughts, every muscle in my arms and legs trembled. My Dr said it was the cataplexy breaking through to continue the dose. Well I stopped it for 2 days and all symptoms disappeared. Itold this to my Dr so now we are back to the lower dose and rising more slowly. I really want this to work.
Working / Worked
Love it! Going on a year.
Working / Worked
Works side effects when i am sleeping
Showing 1 - 10 of 279 Reviews
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  1. Discussion: Xyrem
    i tried Xyrem for a month for the first week and half it was with better sleep but didnt affect my EDS then no effect after that at all. But Hopeful... [More]
  2. Discussion: Xyrem
    Good Morning, Welcome to the group Hicks! Glad to see the Xyrem is working for you! Hopefully it will work for you also jeb1977. I tried Xyrem app... [More]
  3. Discussion: Xyrem
    I am new to this group and this is my first post. Hope I do it right :) I started Xyrem about a month ago. It has made a great and positive diff... [More]
  4. Discussion: Xyrem
    Twelve years on Xyrem - wow! I was under the impression this was a relatively new use of the drug. I am still not having consistent experiences with i... [More]
  5. Discussion: Xyrem
    Yes, I find that the longer I can go without eating prior to taking the Xyrem, the better. I try not to eat after 5 p.m. and then take my first dose a... [More]