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Sodium oxybate is used to reduce the number of cataplexy (weak or paralyzed muscles) attacks in people with narcolepsy. This medicine is available only with your healthcare professional's prescription, and you can only get it from one central pharmacy. Before you use sodium oxybate your healthcare professional shoul... continue

Treatment Success Rate

Top 5 Communities
Condition Members Success
Narcolepsy
187
83%
Fibromyalgia
10
100%
Insomnia
6
100%
Chronic Pain
1
100%
Bipolar Disorder
1
100%
Overall, 85% (210 Members) find Xyrem helpful
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Xyrem Reviews

Show: for
Working / Worked
Taken it for a month. Rough at first but wow! Life changing once I added nuvigil
Working / Worked
Helps me get a deeper sleep at night
Working / Worked
Worked very well for cataplexy but scary, to impossible to function, if, for example need to get up for child, use restroom.
Working / Worked
In the beginning I hardly ever had to take my "stay awake meds". I definitely wake up a lot easier still.
Working / Worked
At full dose over a year
Working / Worked
Only been taking for three weeks, has been life changing. A few side effects especially since I don't use salt anyway.
Working / Worked
I was ecstatic when I started it and was able to get 6 hrs! of sleep. Into the third titrating dose I began to have strange s/e's like blurry and double vision,crazy thoughts, every muscle in my arms and legs trembled. My Dr said it was the cataplexy breaking through to continue the dose. Well I stopped it for 2 days and all symptoms disappeared. Itold this to my Dr so now we are back to the lower dose and rising more slowly. I really want this to work.
Working / Worked
Love it! Going on a year.
Working / Worked
Works side effects when i am sleeping
Working / Worked
Developed severe PLMD after starting Xyrem, never resolved, then developed seizure disorder for years until I connected the drug with the seizures -- quitting Xyrem stopped the seizures. Strange drug.
Showing 1 - 10 of 273 Reviews
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Discussions

  1. Discussion: Xyrem
    I experience all of that. Sleep masks seem to help. Put them on, turn everything off, and make myself close my eyes and put that on and not think. Usu... [More]
  2. Discussion: Xyrem
    Twelve years on Xyrem - wow! I was under the impression this was a relatively new use of the drug. I am still not having consistent experiences with i... [More]
  3. Discussion: Xyrem
    My husband has been on zyrem seems like at least 12 years now. Many interesting stories have come out of this. He had to have his dose increased to 4 ... [More]
  4. Discussion: Xyrem
    Yes, I find that the longer I can go without eating prior to taking the Xyrem, the better. I try not to eat after 5 p.m. and then take my first dose a... [More]
  5. Discussion: Xyrem
    I have been taking Xyrem for about six weeks and would love to find others who take it. I am having odd experiences -- nothing scary or dangerous, jus... [More]