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Hyaluronate sodium derivative is similar to a substance that occurs naturally in joints that helps joints work properly by acting like a lubricant and shock absorber. This medicine is injected into the knee to relieve pain caused by osteoarthritis.

This medicine is to be administered only by or under the immed... continue

Treatment Success Rate

Top 5 Communities
Condition Members Success
Sports Injuries
Rheumatoid Arthritis
Stickler Syndrome
Overall, 69% (93 Members) find Synvisc helpful

Synvisc Reviews

Show: for
Working / Worked
Some relief... but no longer providing long acting relief
Working / Worked
Left knee having trouble with but it always worked in the past for my right knee. No problems since my injections and i walk 10,000 steps a day and climb 10 flights a day...
Working / Worked
It has helped but it caused swelling in lower legs and feet.
Working / Worked
Unguided injections. Raging reaction but no improvement.
Working / Worked
I've had the series of these shots twice and it works great.
Working / Worked
I had the Synvisc One shot. Working ok. Pain has gone down 50%. Others have stated the shots were painful. They should NOT be painful. Freezing spray and a numbing shot before the synvisc shot should be done. I will say the Synvisc one feels like a lot of fluid being injected (knees pressure builds). Needle was in my leg for a good minute or so.
Working / Worked
Very painful injection but it worked well relieving the pain in my knees.
Working / Worked
My insurance would only pay for one series, did help for about 1-2 years.
Working / Worked
Helped a lot. Still have pain. Just can tollerate it now.
Working / Worked
It has helped but the injections are so painful
Showing 1 - 10 of 100 Reviews
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  1. Discussion: Synvisc Injection
    Hi Mary, to tell you the truth, I am now having more pain since the Synvisc injections than before they started. I have had more pain in the knees eve... [More]
  2. Discussion: Synvisc Injection
    Hey Christine, I am starting my third round of Synvisc next Wednesdy. I have the very same thought process as you do; I want to hold off a knee rep... [More]
  3. Discussion: Synvisc Injection
    Nice to hear positive things. I am scheduled to have my knees injected Monday. I will let you know how I do with it. It will be nice to have some pa... [More]
  4. Discussion: Synvisc Injection
    Christine26, How's it going after the Synvisc? Hope it's helping! [More]
  5. Discussion: Synvisc Injection
    Hi, I have just finished having the third dose of a set of three Synvisc injection for too little cartilage in the knee on Thursday. I am beginning to... [More]