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Methotrexate, abbreviated MTX and formerly known as amethopterin, is an antimetabolite drug used in treatment of cancer and autoimmune diseases. It acts by inhibiting the metabolism of folic acid. more at Wikipedia

Treatment Success Rate

Top 5 Communities
Condition Members Success
Rheumatoid Arthritis
665
81%
Lupus
239
70%
Psoriasis
138
82%
Arthritis
96
88%
Crohn's Disease & Ulcer...
90
57%
Overall, 79% (1461 Members) find Methotrexate helpful
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Methotrexate Reviews

Show: for
Working / Worked
takes years to notice a differnce but trips to the hospitla will decrease over time
Working / Worked
been on this three years. take 20 mg a week. doesn't work alone so doing biologics
Working / Worked
Worked with Enbrel but it elevated my liver enzymes after 5 months. I was taken off the drug and started on plaquenil.
Working / Worked
I take this med along with humira and prednisone, the side effects I'm experiencing are thinning hair and purple legs
Working / Worked
This medicine I take in an injection since it will have less side effects, it causes me to have purple/mottled legs that look like bruises - it has caused my hair to thin a great deal
Working / Worked
I am now up to 30mg injections. Much better than the tablets which made me very sick and dizzy.
Working / Worked
seems to help with the lung itching
Working / Worked
Not sure. I was on 7 pills per week, and about a month ago my Rheumy put me on weekly injections. Again, in the middle of the second flare in the last 3 months.
Working / Worked
I am on injections once a week. I believe it has helped a great deal then just the Hydroxychloroquine alone. I have had no side effects so far.
Working / Worked
have been on it since March, 09
seems to be kicking in - I am feeling better
Showing 51 - 60 of 1607 Reviews
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Discussions

  1. Discussion: methotrexate
    I've been on methotrexate for about 6 months now with the only side effect being a little fatigue. It doesn't help me much on its own, but does in co... [More]
  2. Discussion: Methotrexate
    I never took the methotrexate either ,One time I was so fed up with the preedisone I decide to take my self off big mistake I got real sick Fever ch... [More]
  3. Discussion: Methotrexate
    Hi, Renee I have been on methotrexate for almost 2 years now. I was very sick when I was taking the pill form. I had terrible headaches, diahrea, s... [More]
  4. Discussion: Methotrexate
    I HAVE NEVER TAKEN METHOTREXATE MYSELF, BUT I KNOW COMING OFF OF PREDNISONE TOO FAST CAN CAUSE YOU TO FEEL SICK, HAVE JOINT PAIN/ACHES. I KNOW MY DOCT... [More]
  5. Discussion: Methotrexate
    Hi I take methotrexate too. A couple words of wisdom. I was told to take it on a day when I don't have to go anywhere or do anything so that if the M ... [More]

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