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Methotrexate, abbreviated MTX and formerly known as amethopterin, is an antimetabolite drug used in treatment of cancer and autoimmune diseases. It acts by inhibiting the metabolism of folic acid. more at Wikipedia

Treatment Success Rate

Top 5 Communities
Condition Members Success
Rheumatoid Arthritis
665
81%
Lupus
239
70%
Psoriasis
138
82%
Arthritis
96
88%
Crohn's Disease & Ulcer...
90
57%
Overall, 79% (1461 Members) find Methotrexate helpful
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Methotrexate Reviews

Show: for
Working / Worked
It helped somewhat to relieve symptoms. No side effects but did not completely relieve pain
Working / Worked
worked, but liver functions were way too high, had to be removed from it.
must hrlp some; have persevered thru the side effects cuz it's worth it
Working / Worked
helped a bit
Working / Worked
Makes me EXTREMELY NAUSIATED and TIRED.
Working / Worked
Helps the RA exhaustion and I have never had a bad skin flare, so I guess so.
Working / Worked
worked very weel put me in remission recently went back on med 1 week ago
Working / Worked
Take ten pills 1x a week with Humira. Did not work well alone.
Working / Worked
It worked but made me too sick to use.
Working / Worked
She is on this now. I see improvement but she is really sick for the first two days after taking this.
Showing 91 - 100 of 1607 Reviews
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Discussions

  1. Discussion: methotrexate
    I've been on methotrexate for about 6 months now with the only side effect being a little fatigue. It doesn't help me much on its own, but does in co... [More]
  2. Discussion: Methotrexate
    I never took the methotrexate either ,One time I was so fed up with the preedisone I decide to take my self off big mistake I got real sick Fever ch... [More]
  3. Discussion: Methotrexate
    Hi, Renee I have been on methotrexate for almost 2 years now. I was very sick when I was taking the pill form. I had terrible headaches, diahrea, s... [More]
  4. Discussion: Methotrexate
    I HAVE NEVER TAKEN METHOTREXATE MYSELF, BUT I KNOW COMING OFF OF PREDNISONE TOO FAST CAN CAUSE YOU TO FEEL SICK, HAVE JOINT PAIN/ACHES. I KNOW MY DOCT... [More]
  5. Discussion: Methotrexate
    Hi I take methotrexate too. A couple words of wisdom. I was told to take it on a day when I don't have to go anywhere or do anything so that if the M ... [More]

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