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Methotrexate, abbreviated MTX and formerly known as amethopterin, is an antimetabolite drug used in treatment of cancer and autoimmune diseases. It acts by inhibiting the metabolism of folic acid. more at Wikipedia

Treatment Success Rate

Top 5 Communities
Condition Members Success
Rheumatoid Arthritis
1308
81%
Lupus
409
72%
Psoriasis
211
80%
Crohn's Disease & Ulcer...
141
58%
Arthritis
121
86%
Overall, 79% (2649 Members) find Methotrexate helpful
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Methotrexate Reviews

Show: for
Working / Worked
Stopped taking this when the Humira started working.
Working / Worked
worked up up until 6 months ago
Working / Worked
7 years on it. Ive just been pulled off of it due to rise in liver enzymes.
hair fell out'
Working / Worked
took but side effects horrible had to quit
Working / Worked
Was on Methotrexate - came off it as i was not liking the 6 week trip to the lab for blood works + the long term side effects that could happen worried me. I was off Methotrexate for about a year and now i am having problems - flare ups so i am going back on it along with the biological medicine i am taking.
Working / Worked
I have a love/hate relationship with Metho. Love the fact that my inflamation is better, hate the side effects and the fact that it is poison.
Starting this June 2013
Working / Worked
worked before had to stop due to liver. Just started again
Working / Worked
After many sonograms my diagnosis was pregnancy of undetermined location and took this shot. I miscarried a week later.
Showing 1 - 10 of 3091 Reviews
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Discussions

  1. Discussion: methotrexate
    My rheum wants me to consider methotrexate. I wanted to hear from anyone who has taken this medication. How has it affected you good or bad. [More]
  2. Discussion: Methotrexate
    I've used methotrexate for four years now and I still have all my hair :-) I take mine on Sunday evenings (8 tablets now) and I do feel awful the nex... [More]
  3. Discussion: Methotrexate
    Hi All, I started Methotrexate Saturday. I was so scared taking those first 4 pills. Thought I would wake up and find clumps of hair on my pi... [More]
  4. Discussion: Methotrexate
    I was taking methotrexate for a different autoimmune disease, but I was told that it could take 4-6 weeks to take full effect. So I wonder if it's ju... [More]
  5. Discussion: Methotrexate
    Hi All, Does anyone have experience with Methotrexate? Especially with Diamox?? I am to start it once a week today or tomorrow and wondering what... [More]