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Methotrexate, abbreviated MTX and formerly known as amethopterin, is an antimetabolite drug used in treatment of cancer and autoimmune diseases. It acts by inhibiting the metabolism of folic acid. more at Wikipedia

Treatment Success Rate

Top 5 Communities
Condition Members Success
Rheumatoid Arthritis
Crohn's Disease & Ulcer...
Overall, 79% (2961 Members) find Methotrexate helpful

Methotrexate Reviews

Show: for
Currently taking
Working / Worked
I believe this helped, but 1) caused blisters on my hands and 2) caused liver problems. Still taking, but at reduced dosage, and my large joints (hips, shoulders, knees) are killing me.
Working / Worked
i Hate it. Took it for so long that I started to manifset nausea and dizziness at the sight of the shot.
poisoned me.
Working / Worked
I have been on metho for 3 years. I take 7 every week, never had a problem with this drug.
Working / Worked
When first dx, large injection dosage made me way too sick. Now take small injection each week with Orencia. Combination has been the most effective so far.
Working / Worked
Worked along with plaquinelle and folic acid for more than a year then FLARE up now must use strong pks as side affects
Working / Worked
Of all meds so far, seems to work the best. does cause some nausea and fatigue for a day after.
Working / Worked
7 years very well influenced by 15mg per week without problems very good mobility indicators in the norm. Stop activation process without methotrexate exactly two years.
Working / Worked
0.6 ml injection. Minimal side effects including fatigue the day after injection
Showing 1 - 10 of 3469 Reviews
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  1. Discussion: Methotrexate
    Hi! I am concerned about starting methotrexate therapy due to the fact that I am a nurse case manager for two different hospitals and I know tha... [More]
  2. Discussion: Methotrexate
    Has anyone experienced night sweats with methotrexate? [More]
  3. Discussion: methotrexate
    My rheum wants me to consider methotrexate. I wanted to hear from anyone who has taken this medication. How has it affected you good or bad. [More]
  4. Discussion: Methotrexate
    I've used methotrexate for four years now and I still have all my hair :-) I take mine on Sunday evenings (8 tablets now) and I do feel awful the nex... [More]
  5. Discussion: Methotrexate
    Hi All, Does anyone have experience with Methotrexate? Especially with Diamox?? I am to start it once a week today or tomorrow and wondering what... [More]