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Methotrexate, abbreviated MTX and formerly known as amethopterin, is an antimetabolite drug used in treatment of cancer and autoimmune diseases. It acts by inhibiting the metabolism of folic acid. more at Wikipedia

Treatment Success Rate

Top 5 Communities
Condition Members Success
Rheumatoid Arthritis
660
81%
Lupus
239
70%
Psoriasis
138
82%
Arthritis
96
88%
Crohn's Disease & Ulcer...
90
57%
Overall, 79% (1456 Members) find Methotrexate helpful
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Methotrexate Reviews

Show: for
Working / Worked
??? I'm still taking it, and I've been taking it for the past twelve years. It doesn't help my skin, but I'm hoping it's working on my joints.
Working / Worked
not really sure if it helps or not. I do not take the pills or injections but use the injectionable medication mixed with juice.
Working / Worked
Had difficulty with nausea on the pill, have moved to injections. However, it does not seem to be working to control pain, so my doctor is talking about moving me to Remicade infusions.
Working / Worked
Pretty sure it's working...
Working / Worked
Worked pretty quickly.
Working / Worked
worked but made me sick and had sexual side effects
Working / Worked
Works well low dose with Orencia
Working / Worked
works I get worse when I am off of it..hate the hair loss!
Working / Worked
Doesn't seem to be doing the job after 6 months on this dosage. See the doc on Monday and will get more info/ideas.
Working / Worked
I was taken off methotrexate because of liver function concerns.
Showing 1 - 10 of 1600 Reviews
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Discussions

  1. Discussion: methotrexate
    I've been on methotrexate for about 6 months now with the only side effect being a little fatigue. It doesn't help me much on its own, but does in co... [More]
  2. Discussion: Methotrexate
    I never took the methotrexate either ,One time I was so fed up with the preedisone I decide to take my self off big mistake I got real sick Fever ch... [More]
  3. Discussion: Methotrexate
    Hi, Renee I have been on methotrexate for almost 2 years now. I was very sick when I was taking the pill form. I had terrible headaches, diahrea, s... [More]
  4. Discussion: Methotrexate
    I HAVE NEVER TAKEN METHOTREXATE MYSELF, BUT I KNOW COMING OFF OF PREDNISONE TOO FAST CAN CAUSE YOU TO FEEL SICK, HAVE JOINT PAIN/ACHES. I KNOW MY DOCT... [More]
  5. Discussion: Methotrexate
    Hi I take methotrexate too. A couple words of wisdom. I was told to take it on a day when I don't have to go anywhere or do anything so that if the M ... [More]

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