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Methotrexate, abbreviated MTX and formerly known as amethopterin, is an antimetabolite drug used in treatment of cancer and autoimmune diseases. It acts by inhibiting the metabolism of folic acid. more at Wikipedia

Treatment Success Rate

Top 5 Communities
Condition Members Success
Rheumatoid Arthritis
1452
81%
Lupus
443
72%
Psoriasis
220
80%
Crohn's Disease & Ulcer...
147
59%
Arthritis
122
86%
Overall, 79% (2882 Members) find Methotrexate helpful
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Methotrexate Reviews

Show: for
Working / Worked
It decreased pain, required blood tests every three months and did not eliminate the disease. For me, this is unacceptable. I am now free of rheumatoid arthritis and the associated prescription methotrexate.
only just start it this week and it seems to be working so far
Working / Worked
I was put on MTX for one month to get out of months-long flare. It worked!
Working / Worked
Seems to work well.
Working / Worked
didn't make much of a difference, I felt worse on it
Working / Worked
But it changed my personality to where I was angry all the time. Stopped taking it.
Working / Worked
I only notice a slight change if I stop taking it.
Working / Worked
Waste of time and money
Working / Worked
don't know
Working / Worked
Using Oxtrexup now. Better results than taking the pills.
Showing 1 - 10 of 3377 Reviews
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Discussions

  1. Discussion: Methotrexate
    Hi! I am concerned about starting methotrexate therapy due to the fact that I am a nurse case manager for two different hospitals and I know tha... [More]
  2. Discussion: Methotrexate
    Has anyone experienced night sweats with methotrexate? [More]
  3. Discussion: methotrexate
    My rheum wants me to consider methotrexate. I wanted to hear from anyone who has taken this medication. How has it affected you good or bad. [More]
  4. Discussion: Methotrexate
    I've used methotrexate for four years now and I still have all my hair :-) I take mine on Sunday evenings (8 tablets now) and I do feel awful the nex... [More]
  5. Discussion: Methotrexate
    Hi All, Does anyone have experience with Methotrexate? Especially with Diamox?? I am to start it once a week today or tomorrow and wondering what... [More]