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Methotrexate, abbreviated MTX and formerly known as amethopterin, is an antimetabolite drug used in treatment of cancer and autoimmune diseases. It acts by inhibiting the metabolism of folic acid. more at Wikipedia

Treatment Success Rate

Top 5 Communities
Condition Members Success
Rheumatoid Arthritis
Crohn's Disease & Ulcer...
Overall, 79% (2872 Members) find Methotrexate helpful

Methotrexate Reviews

Show: for
Working / Worked
But it changed my personality to where I was angry all the time. Stopped taking it.
Working / Worked
I only notice a slight change if I stop taking it.
Working / Worked
Waste of time and money
Working / Worked
don't know
Working / Worked
Using Oxtrexup now. Better results than taking the pills.
Working / Worked
Had worked until my first flare up now looking at making changes
Working / Worked
doesn't seem to be doing anything except cause side effects from the medication been taking for a little over 2 months
No known side effects from this yet. It is intrathecal, and he had a headache from that once.
Working / Worked
Worked but just had to start injections to get more into my system.
Working / Worked
Took it with Remicaid. Could not continue because my liver enzymes became too high.
Showing 1 - 10 of 3365 Reviews
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  1. Discussion: Methotrexate
    Has anyone experienced night sweats with methotrexate? [More]
  2. Discussion: methotrexate
    My rheum wants me to consider methotrexate. I wanted to hear from anyone who has taken this medication. How has it affected you good or bad. [More]
  3. Discussion: Methotrexate
    I've used methotrexate for four years now and I still have all my hair :-) I take mine on Sunday evenings (8 tablets now) and I do feel awful the nex... [More]
  4. Discussion: Methotrexate
    Hi All, Does anyone have experience with Methotrexate? Especially with Diamox?? I am to start it once a week today or tomorrow and wondering what... [More]
  5. Discussion: Methotrexate
    Taking methotrexate for 2 months. I am now up to the max dosage of 20 mg that my doctor prescribed. The only side effect so far are mouth sores but a ... [More]