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Pyridostigmine is used to treat muscle weakness in people with myasthenia gravis and to combat the effects of curariform drug toxicity. It also has a military use as a nerve gas antidote (it has been used in particular during the first Gulf War). more at Wikipedia

Treatment Success Rate

Top 5 Communities
Condition Members Success
Myasthenia Gravis
Depression - Teen
Overall, 90% (863 Members) find Mestinon helpful

Mestinon Reviews

Show: for
Working / Worked
I never really could tell if it helped. It always had some kind of side effect that I didn't want to deal with.
Working / Worked
Seemed to work as an adjunct therapy to immunosuppressants and prednisone. It has never worked as a primary and only treatment. When I first started taking it my eyes were very watery. This is no longer a problem.
Working / Worked
Only thing that gets me through the day and helps with eating.
Working / Worked
I am on 180mg's per day and it is helping a lot but I am noticing at about the 3-3 1/2 hour mark that I am counting down to my next dose. I typically have a high tolerance to medication. I have not had any side effects.
Working / Worked
mestinon has helped but still needed to add prednisone
Working / Worked
Very little side effects with Mestinon (some stomach upset in the beginning but then I got used to it). It has really helped my eyes straight out (they were previously in opposite directions) although my vision is not 100% yet.
Working / Worked
My life blood....LOL
Working / Worked
Good response
Working / Worked
Just diagnosed with Ocular MG after having it for approximately 1-1/2 to 2 years and not knowing it. Perhaps even longer. No problems with weakness, vision or anything else. It's just that my right eye is closed about 20% less than my left. If I don't look at it in a mirror, I can't tell. Trying to ween myself onto the Mestonin in small doses, but so far having a tough time with the "energy boost" (Like several cups of strong coffee). Other than that, not much of any other side effects.
Working / Worked
Currently taking both regular and time-release dosages. It works to alleviate the symptoms some days better than others.
Showing 31 - 40 of 1002 Reviews
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  1. Discussion: Mestinon
    I have been diagnosed for 2years. Biggest problems are weakness in legs double vision and fatigue. Mestinon does nothing. I'm on 20mg prednisone and 1... [More]
  2. Discussion: mestinon
    Not water. AIR! They dicked around with my mestinon in hospital on discaharge day! I am going to Samar a MG coalition or whatever to allow us to co... [More]
  3. Discussion: mestinon
    Maybe I care too much.....maybe I get too involved.....but anyone here who believes they have MG and are not on mestinon are depriving themselves of... [More]
  4. Discussion: Mestinon
    Thanks Marie, I will add this to our Link's Group under the discussion "Mestinon." The second article is also a good overview of treatment... [More]
  5. Discussion: Mestinon
    I see so many of you discuss Mestinon. What class of med is it? Does it have a lot of side effects? Is it prescribed freely or is it more of a last re... [More]