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Pyridostigmine is used to treat muscle weakness in people with myasthenia gravis and to combat the effects of curariform drug toxicity. It also has a military use as a nerve gas antidote (it has been used in particular during the first Gulf War). more at Wikipedia

Treatment Success Rate

Top 5 Communities
Condition Members Success
Myasthenia Gravis
Depression - Teen
Overall, 90% (902 Members) find Mestinon helpful

Mestinon Reviews

Show: for
Working / Worked
I was just diagnosed and they put me on mestinon 60, mg 3x a day so no more double vision I am so exhausted. going back to neurologist on the 18th
Working / Worked
My MG wonder drug. Works great for my balbar MG. No side effects to speak of.
Working / Worked
Just beginning Mestinon. It was working well to stabilize until a stressful weekend and I am turned upside down.
Working / Worked
I was only on it for about a month & my symptoms became worse so the Neuro-Opthamologist took me off it! I had uncontrollable diarrhea & unable to eat.
Working / Worked
Been using since 1997.
Working / Worked
Mestinon has been my friend and my enemy. I've been taking it since the start of my diagnosis. What started as simply 60mg/ 3x day is now Mestinon TimeSpan 180mg/ 4x a day. It gives me stomach aches if I take it on an empty stomach. I get muscle twitches periodically and increased salivation, too.
Working / Worked
I started Mestinon about 3 weeks ago, taking 60 mg. every 4 times a day but my Dr. told me to not take the last dose too late in the day. I actually thought I could cut back on it because my eye wasn't drooping at all before I needed to take another one. I had an EMG on Tuesday and everything has changed. The test on my arm was extremely painful (I've had shoulder issues forever from a rotator cuff surgery years ago. The test was normal. However, I feel worse than before the test.
Working / Worked
maintenence works for a while
Working / Worked
Working / Worked
seems to work ok but side effects heavy
Showing 1 - 10 of 1049 Reviews
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  1. Discussion: Mestinon
    Mestinon is the most effective treatment for the symptoms of MG. While everyone is unique, in general, very few of the potential side effects are expe... [More]
  2. Discussion: Mestinon
    I understand. Finding out that you have MG is overwhelming. Stay close to this group. Ask a lot of questions, and be your own advocate. Eat a sm... [More]
  3. Discussion: Mestinon
    Hi GrecoGirl, Welcome to our wonderful group. I've been on only Mestinon for 2.5 years, first at 60mgx3 and then 60x4 for just over a year. I am s... [More]
  4. Discussion: MESTINON
    Every MG patient requires individual dosing with Mestinon. The goal is to find the lowest "effective" dose. Mestinon has many side effects t... [More]
  5. Discussion: mestinon
    Maybe I care too much.....maybe I get too involved.....but anyone here who believes they have MG and are not on mestinon are depriving themselves of... [More]