Kaletra

The proper way to use

A paper with information about lopinavir and ritonavir will be given to you with your filled prescription. Read this paper carefully and ask your health care professional if you need additional information or explanation.

It is important that lopinavir and ritonavir capsules and oral solution be taken with food.

Lopinavir and ritonavir tablets may be taken with or without food.

For oral solution dosage form, use calibrated dosing syringe to measure dose.

For tablet dosage form, swallow whole and do not crush or chew.

Take this medicine exactly as directed by your doctor. Do not take it more often and do not take it for a longer time than your doctor ordered. Also, do not stop taking this medicine without checking with your doctor first.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (capsules):
  • For treatment of HIV infection:
    • Adults: 400 milligrams (mg) of lopinavir and 100 mg of ritonavir (3 capsules) twice a day with food or 800 mg of lopinavir and 200 mg of ritonavir (6 capsules) one time a day with food.
    • Children: This dosage form is usually not used for children. Please refer to the oral solution dosage form.
• For oral dosage form (oral solution):
  • For treatment of HIV infection:
    • Adults and adolescents: 400 mg of lopinavir and 100 mg of ritonavir (5 milliliters [mL]) twice a day with food or 800 mg of lopinavir and 200 mg of ritonavir (10 mL) one time a day with food.
    • Children 6 months to 12 years of age: Dose is based on body weight and must be determined by your doctor.
    • Children less than 6 months of age: Use and dose must be determined by your doctor.
    • Use and dose must be determined by a doctor for all children receiving the once-daily dose.
  • For oral dosage form (tablets):
    • For treatment of HIV infection:
      • Adults: 400 milligrams (mg) of lopinavir and 100 mg of ritonavir (2 tablets) twice a day with food or 800 mg of lopinavir and 200 mg of ritonavir (4 tablets) one time a day with or without food.
      • Children: This dosage form is usually not used for children. Please refer to the oral solution dosage form.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store in the refrigerator. Do not freeze.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.