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(also known as Norpramin, Pertofrane)
Desipramine is a tricyclic antidepressant (TCA) that inhibits the reuptake of norepinephrine. It is sold under the brand names Norpramin© and Pertofrane©. It is used to treat depression, but not considered a first line treatment since the introduction of SSRI antidepressants. more at Wikipedia

Treatment Success Rate

Top 5 Communities
Condition Members Success
Depression
288
44%
Bipolar Disorder
8
88%
Depression - Teen
3
100%
Fibromyalgia
1
100%
Gay & Lesbian Teens
2
100%
Overall, 49% (315 Members) find Desipramine helpful
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Desipramine Reviews

Show: for
Somewhat Helpful
No longer taking this
Somewhat Helpful
When I was on it I wasn't too depressed, and it did help a bit, but it also made me wicked dizzy all the time.
Somewhat Helpful
I took this one for a long time many years ago. It helped some, but I find newer drugs more effective.
Somewhat Helpful
Moving of Peroxitine, to
Somewhat Helpful
bad side effects
Somewhat Helpful
Took about 20 years ago as my first AD, didn' help much, just killed my sex life.
Somewhat Helpful
I still have good and not so good days i pretty well know from the moment i wake up , what kind of day i'm going to have.although i am in Theraphy i think a good support group, could be benificial
Somewhat Helpful
Still was not enough relief
Somewhat Helpful
Before the SSRI's this was the best drug. Side effects of irregular heart rate.
Somewhat Helpful
It was over 25 yrs ago so I don't really rember
Showing 71 - 80 of 290 Reviews
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Discussions

  1. Discussion: Desipramine
    I switched off desipramine....Im now taking effexor (6 days) but its not working yet. How long did it take for the zoloft to work? [More]
  2. Discussion: Desipramine
    I had taken Desipramine about a year and a half ago. I was actually up to a 300mg dose. It made me feel "just" good enough to return to work... [More]
  3. Discussion: Desipramine
    I was wondering if anyone has tried desipramine and if it worked. Im very depressed and I started it along with zyprexa 1 week ago and Im not sure if... [More]
  4. Discussion: Desipramine
    I was wondering if anyone else has tried desipramine for post partum. I was prescribed it 6 days ago for depression/panic attacks and I felt worse th... [More]
  5. Discussion: Desipramine
    Hey BonnieC Its interesting in the past couple years Desipramine (brand name Norpramin in the US) has been studied most for depression in the elderly... [More]

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