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(also known as Norpramin, Pertofrane)
Desipramine is a tricyclic antidepressant (TCA) that inhibits the reuptake of norepinephrine. It is sold under the brand names Norpramin© and Pertofrane©. It is used to treat depression, but not considered a first line treatment since the introduction of SSRI antidepressants. more at Wikipedia

Treatment Success Rate

Top 5 Communities
Condition Members Success
Depression
288
44%
Bipolar Disorder
8
88%
Depression - Teen
3
100%
Fibromyalgia
1
100%
Gay & Lesbian Teens
2
100%
Overall, 49% (315 Members) find Desipramine helpful
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Desipramine Reviews

Show: for
Working / Worked
Not sure??
Working / Worked
I take 100mg 30min before i goto sleep. It decreases the amount that i dream and makes me able to actually wake up after 9 to 10hours of sleep instead of the 12 to16hrs needed to kind of function before.. I can function on 6 or 8 hours if i NEED to which is drastically different than my usual state. I also wake up to external stimuli too like the phone ringing or a knock at the door. unlike before when i would sleep through earth quakes. Ive been on it a year and its a total life saver.
Working / Worked
shakacaw
Working / Worked
took this years ago
Working / Worked
continue to take have been on for about a year. Would have to say I am better than a year ago but a lot has happened in that year.
Working / Worked
Worked pretty well but then gave out on me. Was on it several times.
Working / Worked
have been taking it for 20 years doesnt seem to work no more
Working / Worked
Liked it; but short term memory started to fade and I was getting confused (more than normal! lol)
Working / Worked
at 1x, no longer using
Working / Worked
Sexual side effects i think. otherwise worked well for depression
Showing 1 - 10 of 290 Reviews
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Discussions

  1. Discussion: Desipramine
    I switched off desipramine....Im now taking effexor (6 days) but its not working yet. How long did it take for the zoloft to work? [More]
  2. Discussion: Desipramine
    I had taken Desipramine about a year and a half ago. I was actually up to a 300mg dose. It made me feel "just" good enough to return to work... [More]
  3. Discussion: Desipramine
    I was wondering if anyone has tried desipramine and if it worked. Im very depressed and I started it along with zyprexa 1 week ago and Im not sure if... [More]
  4. Discussion: Desipramine
    I was wondering if anyone else has tried desipramine for post partum. I was prescribed it 6 days ago for depression/panic attacks and I felt worse th... [More]
  5. Discussion: Desipramine
    Hey BonnieC Its interesting in the past couple years Desipramine (brand name Norpramin in the US) has been studied most for depression in the elderly... [More]

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