Azilect

What you should know before using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatrics

Appropriate studies have not been performed on the relationship of age to the effects of rasagiline in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of rasagiline in the elderly.

Breast Feeding

Studies suggest that this medication may alter milk production or composition. If an alternative to this medication is not prescribed, you should monitor the infant for side effects and adequate milk intake.

Drug Interactions

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Amphetamine
• Cyclobenzaprine
• Dextromethorphan
• Duloxetine
• Ephedrine
• Fluvoxamine
• Lisdexamfetamine
• Meperidine
• Methadone
• Mirtazapine
• Morphine
• Morphine Sulfate Liposome
• Phenelzine
• Phenylephrine
• Phenylpropanolamine
• Propoxyphene
• Pseudoephedrine
• St John's Wort
• Tramadol

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Tyramine Containing Food

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Mild liver problems—May cause an increased amount of rasagiline in your blood. Your doctor may lower your dose

• Moderate or severe liver problems—This medicine SHOULD NOT be used because it may cause an increased amount of rasagiline in your blood

• Pheochromocytoma (tumor on the adrenal gland)—This medicine SHOULD NOT be used.