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The proper way to use

For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your health care professional. Taking too much of this medicine may increase the chance of unwanted effects.

Do not take diclofenac and misoprostol combination with magnesium-containing antacids. Antacids may be taken with diclofenac and misoprostol combination, if needed, to help relieve stomach pain, unless you are otherwise directed by your doctor. However, do not take magnesium-containing antacids, since they may cause diarrhea or worsen the diarrhea that is sometimes caused by the diclofenac and misoprostol combination.

Do not chew, crush, or dissolve tablets.

Do not give this medication to another person.

Diclofenac and misoprostol combination should be taken with meals.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablets):
    • For osteoarthritis:
      • Adults—1 tablet of Arthrotec 50 three times a day.
      • Children—Use and dose must be determined by your doctor.
    • For rheumatoid arthritis:
      • Adults—1 tablet of Arthrotec 50 three or four times a day.
      • Children—Use and dose must be determined by your doctor.
    • For osteoarthritis or rheumatoid arthritis (for patients who are unable to tolerate other doses):
      • Adults—1 tablet of Arthrotec 50 two times a day or 1 tablet of Arthrotec 75 two times a day.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.


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