I have been sick nearly 4 years, …
I have been sick nearly 4 years, and have recently received some diagnosis. The crazy thing is the doc said …
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Ali5tair 
Preparation of an isotonic (296 mOsm), alkaline pH drinking water solution for Ali5tair
Caution - You will have to get these numbers checked by an Older Chemist, the ones who were taught how to do balanced 300mOsm (milli-osmols) equations as I have cut out ¾ ers of the NaCl.
Some people wanted to know my isotonic, alkaline drinking water recipe so here it is.
Aim: to prepare an alkaline water which is isotonic, mildly alkaline (pH 7.5 to 8.5) and will help to boost magnesium & hopefully calcium levels as well as make the drinking water more acceptable for a strained gastrointestinal tract (IBS-d) Cat 6 or 7
Background information:
- Al is low magnesium, low calcium and low cobalt
Al has Heavy Metal Poisoning, Mercury Lead and Tin..
- A solution which is isotonic to human cells will have the same concentration of “non-penetrating” molecules as human cells. The key number for this is 300mOsm (milli-osmols).
- Tap water in the area has a pH of around 5 due to the acidic soils of the area.
- Ideally the solution would be as close as possible to a ratio of:
Na: Ca: Mg: Cl 1.15: 0.02: 0.05: 1.48 which represents a saline bag but is un palatable due to the high NaCl Common Salt level (which would induce diarrhea) so you cut the NaCl by ¾ ers and replace the mOsm equivalent with a potassium salt or a magnesium salt depending on what you are deficient off.
- Ideally the solution would be made from NaCl, NaHCO3, K2CO3, Mg (HCO3) 2, MgSO4, and KOH
Methodology:
- For practicality, use only common salt (NaCl), sodium bicarbonate (NaHCO3) & Epsom salts (MgSO4). This is because these are readily available at most supermarkets. The resultant solution will achieve most of the aims of the exercise without supply problems.
- Start with “normal saline”, which is 0.15M NaCl (8g/L). Since salt dissociates into Na+ & Cl-, this means 0.15 x2 = 0.3M (ie 300mOSm). From there modify to include the other 2 components in the desired ratio. You have to decrease the Na Cl by ¾ ers.
- Initially tried 8000mg salt, 500mg sodium bicarb & 500mg Epsom salts
o Outcome: pH around 8.5 or so; perfect
o Outcome: osmolality; 274+12+4 = 290 mOSM. Probably close enough
o Outcome: molar ratio: (want 23 times as much Na as Mg [1.15:0.05], ignoring Ca & Cl). End up with 67 times as much, due to doing calculations based on total weights, not weights of the metals, not helped by the MgSO4 having a lot of water in the crystal; MgSO4.7H2O.
But was un palatable so
Then “modified saline”, which is 0.0375M NaCl (2g/L). 0.0375M x 2 = 0.075M (ie 075.0mOSm)
- Then tried 2000mg salt, 500mg sodium bicarb & 500mg Epsom salts
o Outcome: pH around 8.0 or so; perfect
o Outcome: osmolality; 75+12+4 = 91 mOsm which is 209 mOsm short of isotonic so you have to add @ 1 gram of (Molar mass of K2CO3 = 138.2055 g/mol) plus you have to add @ 0.6 gram of KOH (is 56.1057 g/mol).
- So now the equation is 75+12+4+138+67 = 296 mOSM which is probably close enough to 300mOSm the key number for “non-penetrating” molecules is therefore isotonic to human cells, neither hypertonic nor hypotonic.
The trich is getting pure K2CO3 and KOH in powder form of salts. A good Chemist wil be able to order it for you.
o Outcome: molar ratio: (want 6.5 (6point5) times as much Na as Mg [0.2875 : 0.05], ignoring Ca & Cl). End up with 17 times as much, due to doing calculations based on total weights, not weights of the metals, not helped by the MgSO4 having a lot of water in the crystal; MgSO4.7H2O.
- Recommendation: can add more Epsom salts to bring the ratio to 23:1 (This will improve the osmolality at the same time, up to 298mOsM).
Final protocol still needs refining and is still approximate:
For each litre of tap water, add:
- 2g Sodium Chloride Na Cl common salt/Litre water
@ 0.5g Sodium bicarb (sodium hydrogen carbonate) NaHCO3 to adjust the pH/Litre water (it depends what the pH of the tap water you start with is).
- 1.5g Epsom salts magnesium sulfate MgSO4 /Litre water
and replace the mOsm equivalent with a potassium salt or a magnesium salt depending on what you are deficient off
plus
-__@1g___Potassium Carbonate K2CO3 /Litre water
plus
-__@0.6g_Potassium Hydroxide KOH /Litre water
or
- a heavier Magnesium salt like Magnesium Carbonate MgCO3 is 84.3141 g/mol
by the correct gram ratio instead of K2CO3 and KOH.
I make up 20 litres of water at a time to make its easier in measuring and therefore more accurate due a tighter error limit when measuring out the salts using my scales.
20 litres of water on a hot day (+38 Deg Celsius) lasts me 2 days, on a cold day () Deg Celsius lasts me 4 days.
http://www.ouhscphysio.org/humanph...
Caution - You will have to get these numbers checked by an Older Chemist, the ones who were taught how to do balanced 300mOsm (milli-osmols) equations as I have cut out ¾ ers of the NaCl.
Some people wanted to know my isotonic, alkaline drinking water recipe so here it is.
Aim: to prepare an alkaline water which is isotonic, mildly alkaline (pH 7.5 to 8.5) and will help to boost magnesium & hopefully calcium levels as well as make the drinking water more acceptable for a strained gastrointestinal tract (IBS-d) Cat 6 or 7
Background information:
- Al is low magnesium, low calcium and low cobalt
Al has Heavy Metal Poisoning, Mercury Lead and Tin..
- A solution which is isotonic to human cells will have the same concentration of “non-penetrating” molecules as human cells. The key number for this is 300mOsm (milli-osmols).
- Tap water in the area has a pH of around 5 due to the acidic soils of the area.
- Ideally the solution would be as close as possible to a ratio of:
Na: Ca: Mg: Cl 1.15: 0.02: 0.05: 1.48 which represents a saline bag but is un palatable due to the high NaCl Common Salt level (which would induce diarrhea) so you cut the NaCl by ¾ ers and replace the mOsm equivalent with a potassium salt or a magnesium salt depending on what you are deficient off.
- Ideally the solution would be made from NaCl, NaHCO3, K2CO3, Mg (HCO3) 2, MgSO4, and KOH
Methodology:
- For practicality, use only common salt (NaCl), sodium bicarbonate (NaHCO3) & Epsom salts (MgSO4). This is because these are readily available at most supermarkets. The resultant solution will achieve most of the aims of the exercise without supply problems.
- Start with “normal saline”, which is 0.15M NaCl (8g/L). Since salt dissociates into Na+ & Cl-, this means 0.15 x2 = 0.3M (ie 300mOSm). From there modify to include the other 2 components in the desired ratio. You have to decrease the Na Cl by ¾ ers.
- Initially tried 8000mg salt, 500mg sodium bicarb & 500mg Epsom salts
o Outcome: pH around 8.5 or so; perfect
o Outcome: osmolality; 274+12+4 = 290 mOSM. Probably close enough
o Outcome: molar ratio: (want 23 times as much Na as Mg [1.15:0.05], ignoring Ca & Cl). End up with 67 times as much, due to doing calculations based on total weights, not weights of the metals, not helped by the MgSO4 having a lot of water in the crystal; MgSO4.7H2O.
But was un palatable so
Then “modified saline”, which is 0.0375M NaCl (2g/L). 0.0375M x 2 = 0.075M (ie 075.0mOSm)
- Then tried 2000mg salt, 500mg sodium bicarb & 500mg Epsom salts
o Outcome: pH around 8.0 or so; perfect
o Outcome: osmolality; 75+12+4 = 91 mOsm which is 209 mOsm short of isotonic so you have to add @ 1 gram of (Molar mass of K2CO3 = 138.2055 g/mol) plus you have to add @ 0.6 gram of KOH (is 56.1057 g/mol).
- So now the equation is 75+12+4+138+67 = 296 mOSM which is probably close enough to 300mOSm the key number for “non-penetrating” molecules is therefore isotonic to human cells, neither hypertonic nor hypotonic.
The trich is getting pure K2CO3 and KOH in powder form of salts. A good Chemist wil be able to order it for you.
o Outcome: molar ratio: (want 6.5 (6point5) times as much Na as Mg [0.2875 : 0.05], ignoring Ca & Cl). End up with 17 times as much, due to doing calculations based on total weights, not weights of the metals, not helped by the MgSO4 having a lot of water in the crystal; MgSO4.7H2O.
- Recommendation: can add more Epsom salts to bring the ratio to 23:1 (This will improve the osmolality at the same time, up to 298mOsM).
Final protocol still needs refining and is still approximate:
For each litre of tap water, add:
- 2g Sodium Chloride Na Cl common salt/Litre water
@ 0.5g Sodium bicarb (sodium hydrogen carbonate) NaHCO3 to adjust the pH/Litre water (it depends what the pH of the tap water you start with is).
- 1.5g Epsom salts magnesium sulfate MgSO4 /Litre water
and replace the mOsm equivalent with a potassium salt or a magnesium salt depending on what you are deficient off
plus
-__@1g___Potassium Carbonate K2CO3 /Litre water
plus
-__@0.6g_Potassium Hydroxide KOH /Litre water
or
- a heavier Magnesium salt like Magnesium Carbonate MgCO3 is 84.3141 g/mol
by the correct gram ratio instead of K2CO3 and KOH.
I make up 20 litres of water at a time to make its easier in measuring and therefore more accurate due a tighter error limit when measuring out the salts using my scales.
20 litres of water on a hot day (+38 Deg Celsius) lasts me 2 days, on a cold day () Deg Celsius lasts me 4 days.
http://www.ouhscphysio.org/humanph...
Please get it checked by a Chemist you trust.
Cheers, Chin Chin, Skol, Slovange, bottoms up,
Al
Cheers, Chin Chin, Skol, Slovange, bottoms up, Al
Comments
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Um Al, are you supposed to be making this stuff for yourself???? Seems a bit complicated, huh????
DarlaC
That was polite, Darla. Even one my most brilliant day in history I'm not sure I could have done this. Ok, I could have added the epsoms salts. I throw them in my bath.
Menemsha
I think I'll just go have a beer, lol! Hope you're feeling a little better, Al!
lobeliapeppergrass