The Healing Potential of Universal GI binder

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The familiar homily, \A stitch in time saves nine\ truly applies to gastrointestinal (GI) binders. GI binders latch on to toxic chemicals and toxins, rendering them inactive and enabling us to excrete them safely. Dig up further about coq10 by going to our thrilling encyclopedia. In the simple act of binding toxins, they are a powerful aid to our own detoxification system, not only in the level of the intestine, but also in the kidneys and liver, and in a cellular level within all our cells.

Although we understand the importance of gut health, many are not aware of the mechanisms by which gut health impacts detoxification. Toxins, such as heavy metals and pesticides or herbicides, are irritating to the mucosal lining of the GI tract and result in inflammation.1,2,3,4 An inflamed gut lining shortly becomes \leaky\--allowing bacterial toxins seep into the bloodstream, where they excite our body's inflammatory reaction.5,6 Bacterial endotoxins, and the cascade of inflammatory cytokines they trigger, can also damage the liver and gut, further impairing detoxification.7,8 Exposure to endotoxin also has an effect on detoxification directly, downregulating critical Phase III transporters, the pumps that serve to transport toxins out of our cells and body -- causing us to become even more poisonous.9,10 Endotoxin and the associated inflammation also leads to glutathione depletion, which contributes to even more damage because we are no longer are able to transport toxins from the cells or shield them from the increased oxidative stress and damage.11,12 What a vicious cycle!

But GI binders can offset all that. Tried and true natural binders such as activated charcoal and clay have been used for centuries as remedies for stomach upset, minor food poisoning, and to promote intestinal cleansing.13 Binders are really a powerful tool in our curing armamentarium, for they could detain this spiral of inflammation and impaired detoxification until it begins. They are a basic first step to repairing our detoxification channels - encouraging our ability to excrete toxins and thus restoring our own cleansing systems.

Not all binders are created equal. There isn't any universal toxin binder which has an equal affinity for all toxins--bacterial, heavy metal, mold and more. We could line up a pharmacopeia of binders on our kitchen countertop, but which would we choose, and when? A comprehensive blend of GI binders, carefully selected to provide effective coverage for a selection of common toxins and toxic heavy metals, is a simple and effective approach. Because binders, like charcoal, in their can contribute to constipation, it can be beneficial to improve them with additional elements that help bulk up the stool, soothe the intestinal lining, and support the balance of healthy gastrointestinal flora for normal motility and function. Here follows a brief list of gentle but potent binders that together offer unparalleled synergy and potency.

*Activated Charcoal. Learn new info on a partner use with by browsing to best probiotics information. The use of activated charcoal to bind toxins dates back to the 1800s. In 1831, a French physician took a lethal dose of the poison strychnine, standing before the French Academy of Medicine, and suffered no ill effects because he also consumed charcoal at the same time.14 Since that time, the adsorbing capability and clinical advantages of charcoal have been well described.15 Activated charcoal effectively adsorbs pesticides and herbicides,16 mold toxins,17 endotoxin,18 and more.

Along with its adsorptive properties, charcoal has demonstrated benefits during infections where a person's powerful inflammatory response to a pathogen is potentially damaging. Charcoal has been shown to adsorb and remove the inflammatory molecules associated with the immune response (such as interleukins and tumor necrosis factor) which are primary contributors to cellular damage.19 Research suggests it could be useful as an adjunctive treatment for this reason in configurations of disease.20


*Bentonite Clay. Bentonite clay is also referred to as Montmorillonite clay, for the area in France where it was first found.21 The use of healing clays dates back to ancient civilizations in the Andes, who carried balls of clay for consuming at will, to protect against poisons and toxins.22 Bentonite clay easily absorbs fluids and their toxins also, expanding in quantity. Bentonite clay is particularly good at absorbing aflatoxin, a mold toxin often found in peanuts and on certain grains,23 pesticides and herbicides,24 and cyanotoxins, found in lakes polluted by harmful algal blooms.25 Bentonite clay also has inherent broad-spectrum antibacterial properties and has a healing effect on the gastrointestinal lining.26

*Chitosan. Derived from shellfish, chitosan is caused by enzymatic treatment of chitin, a part of the shell. Chitin has been utilized since ancient times, and these instructions can be found in a book of medicine dating back to the Ming Dynasty: \Split a crab shell, grind it, make a chunk out of it and consume it to take care of anything that swells or grows.\ 27 Chitosan is composed of long-chain sugars known as oligosaccharides and has a prebiotic effect, promoting the development of friendly Bifidobacterium and Lactobacillus gastrointestinal flora.28 Chitosan can bind into the bile salts which emulsify fat, and thus serves to reduce fat absorption.29 More importantly where detoxification is concerned, in addition, it binds and eliminates the conjugated toxins present in bile salts. Chitosan binds to many metals as well as polychlorinated biphenyls (PCBs), phthalates, and bisphenol A (BPA), chemicals with many known adverse effects on health that we are broadly exposed to in the environment.30,31,32,33 Like bentonite clay, chitosan may be a beneficial approach to bacterial infection also, inhibiting the growth of Staphylococcus aureus in one study.34 Chitosan has been shown to have some protective effects against mercury-induced genotoxicity.35

*IMD. The Intestinal Metals Detox (IMD) is a proprietary product which consists of processed silica with covalently attached thiolic metal-binding groups. Visiting in english likely provides tips you might use with your co-worker. This proprietary thiol-functionalized silica delivers insoluble thiol groups to bind and remove mercury and other heavy metals accumulated in the intestines, also directly quenching free-radicals. Both the silica base as well as the binding agents out-compete other compounds for metals in the intestines. I discovered best probiotics by browsing books in the library. IMD does not enter the bloodstream, and thus it will not lead to redistribution or surges of mobilized metals that can potentially lead to kidney/liver overload.

Using thiolated resins dates back to the 1970s when they were used to address methylmercury (MeHg) poisoning in Iraq, and were found to significantly lower the half-life of MeHg from 61 to 20 days, performing even better than penicillamine, a medical metal chelating agent.36,37 IMD intercepts MeHg and other metals trapped in enterohepatic circulation, binding them and escorting them from the intestines.38 By doing so, this allows organ and tissue bound mercury to safely drain into the blood at a natural rate.

*Aloe and Acacia Gum. Both aloe and acacia gum are soothing and healing to the gastrointestinal tract, and can offset the constipation that can occasionally occur with the use of GI binders. Acacia gum contains water-soluble dietary fibers that have a prebiotic effect, stimulating the growth of friendly Bifidobacterium and Lactobacillus bacteria in the gut, in addition to improving levels of butyrate, a short-chain fatty acid with anti-inflammatory effects that also helps reduce intestinal permeability.39,40 Bifidobacteria support the reduction of the damaging endotoxin, and normalize gut function, reducing irritation and inflammation.41,42 Acacia gum also has antioxidant and free-radical scavenging activity.43 As a prebiotic fiber it's well tolerated at high doses with significantly less symptoms than other prebiotics such as fructooligosaccharide (FOS).

Aloe vera is best known for the calming effect it has, commonly being found around many households and used topically for mild burns to the skin. The topical soothing properties aren't only experienced by the skin, and it has a long history of usage for various gastrointestinal conditions associated with inflammation: peptic ulcer disease, gastritis, and inflammatory bowel disease.44,45,46 Aloe vera gel has been shown to have immunomodulatory, antioxidant, and anti inflammatory consequences, which may support healing in a number of settings.47,48,49.