”I'd like a doctor's opinion about new Oxycontin "OP": why are real chronic pain patients suffering so much?
I've had RSD for over 11 years and am severely allergic to any other long acting opiate pain reliever. I never got sick on the old formula and now this new one that is to prevent abuse is making me very ill, is less effective in pain control, and I would like to know what doctors opinions are on this subject as true chronic pain patients seem to be the ones who are suffering the most due to this change.”
Every week we read about a comedian, actress, spokesperson or athlete who has overdosed on prescription drugs, often OxyContin. Most of us also know someone who suffers from chronic pain where oral opiates provide the only hope for a pain free life. There is proper use and there is misuse, and nobody can argue with that.
This question from a DS user with chronic pain is a good one: how do physicians feel about the new OxyContin “OP” which may replace previous forms of OxyContin and hopefully make abuse less easy? Well, if this really is a bioequivalent formulation (a drug with the same active properties) I like it.
On April 5, 2010, Purdue Pharma and the FDA announced the approval of a new formulation of OxyContin (controlled-release oxycodone) oral tablets. Purdue elected to change the drug in an effort to make the tablet more difficult to manipulate for the purpose of intentional misuse and abuse. The reformulated OxyContin is supposed to prevent the medication from being cut, broken, chewed, crushed, or dissolved to release more medication.
OxyContin is such a popular drug of abuse and misuse because of its controlled-release properties; this means each OxyContin tablet contains a large quantity of oxycodone. With the previous formulation you could release high levels of oxycodone all at once, a situation that contributed to a high rate of abuse as well as increased the potential for fatal overdose.
The new formulation (OxyContin OP) has met the FDA criteria for bioequivalence to the original formulation so it should have the same effectiveness and same side effects. Purdue Pharma has started shipping the reformulated OxyContin product and the company will cease shipping the original formulation. So, the previous OxyContin tablets (OxyContin “OC”) will no longer exist.
This was a change made without any evidence. In other words, no evidence currently exists to show that this reformulation of OxyContin is less subject to misuse, abuse, overdose, or addiction. The FDA is requiring Purdue Pharma to conduct a postmarket study to help determine whether the new formulation reduces the drug's abuse and misuse. I would also add that if you are having side effects with this formulation your doctor should report it to Purdue Pharma.