Primary Care Physician
Dr. Orrange received her BA in Biology at the University of California, San Diego, and a Masters Degree in Health Sciences at the Johns Hopkins University School of Public Health. She received her MD from the USC Keck School of…
The Gardasil HPV Vaccine Revisited, Thanks to Michael Douglas
Posted in HPV by Dr. Sharon Orrange on Jun 19, 2013
This past week, these are the questions I’ve been getting from my patients about HPV. Here we go again because we’ve heard about head and neck cancer and HPV. HPV can be a big deal, so here's what you need to know about the Gardasil HPV Vaccine:
1. What does the vaccine do? In an HPV naïve person, the vaccine protects you from the strains of HPV that cause genital warts and abnormal cervical cells (cervical dysplasia and thus cervical cancer). The Gardasil is a quadrivalent vaccine (meaning it protects against 4 HPV genotypes 6/11/16/18). Types 16 and 18 are associated with the majority of cervical cancers and 6 and 11 are associated with the majority of genital warts.

2. How does the vaccine work? Gardasil contains inactive HPV proteins which produce antibodies to prevent cervical cancer and genital warts (also vaginal and vulvar neoplasia, among other HPV related illnesses).

3. Who should get the vaccine? Children older than 9 and adults less than 26. Interestingly, Canadian labeling is aged 9-45. You can begin the series anytime between the ages of 13-26. The goal in vaccinating men obviously is to decrease the transmission rate from men to women and to protect men from HPV related disease.

4. What are the screening tests for men and women? There are no screening tests for men with the exception of anal pap smears in men who have sex with men (and the effectiveness of that is still being investigated). In women we can do HPV DNA testing on cervical cells during your pap smear.
- Dr O.


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Michael Douglas is very brave and it's admirable for him to come out so publically about HPV. I wish more celebrities would admit to having had this because it would help lift the social stigma of what is essentially warts in the genital region. Well done Michael Douglas!
By wartman  Oct 10, 2013
He commented first last year ,we agreed with him the ones that we work in a Cancer Center, we knew about this cancer and others that have to do a lot with their sexual lives.
People have come to the center to be tested.
Also there are paps done for gay men, this cancers are preventable and real facts need to be learned.
He made a big favor to many, when he could have kept this private.
By deraming  Jun 21, 2013
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