Primary Care Physician
Dr Orrange received her BA in Biology at the University of California San Diego and a Masters Degree in Health Sciences at the Johns Hopkins University School of Public Health She received her MD from the USC Keck School of…
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Oh My Aching Knee. A Stepwise Approach to Treating Osteoarthritis.
Posted in Back Pain by Dr. Sharon Orrange on Jan 22, 2009

In 2000, 25 million Americans had osteoarthritis. When arthritis becomes symptomatic in the knee, and it does in 13% of adults over the age of 55, it can impair mobility and be disabling.


Doubts about the safety of some recently prescribed medications like Vioxx and our lack of options for treatment of knee pain from osteoarthritis lends itself to frustration for many of us.Treament is often pain meds and anti-inflammatories, waiting, and eventual referral to knee replacement surgery.


There is a great demand for nonpharmacologic therapy and I think there are good options to consider before starting on meds and surgery. What are the current treatment and management options for arthritis of the knee?


Most studies for osteoarthritis are done looking at the effect of drug treatment and surgery and other conservative measures are often overlooked: exercise, braces, weight loss, and orthotics for example. It seems to make sense that we should start with the above mentioned interventions and leave the medications and drugs if those fail.


Having that in mind here is a stepwise approach to the treatment of osteoarthritis of the knee and hip with the goal being to reduce pain and improve mobility.


First: This is not easy but start with nonpharmacologic therapy including education, exercise, appropriate footwear, weight loss, appliances like insoles (lateral wedged insoles, etc) and knee braces. Exercise includes regular aerobic, muscle-strengthening and range of motion exercises which can be done on your own or taught to you by a physical therapist. Exercises in water can also be effective. If your primary care physician doesn’t help you find these options try and find an orthopedic surgeon to send you in the right direction.


Second: Start gently when you do need pharmacologic therapy. Acetaminophen (Tylenol) is a good start and usually comes in 500 mg or 650 mg tablets for arthritis and up to 4 grams a day can be taken. If this works for you it’s a good and safe long term option and works especially well if taken at night to help fight off the morning stiffness and pain.


Third: Topical applications of NSAIDS (non steroidal anti-inflammatories) and capsaicin work well and are safe to use. The topical preparations like Voltaren you rub on twice a day and they do work well for knee osteoarthritis and you skip most of the side effects of oral medications.


Fourth: When Tylenol doesn’t work it is reasonable to go to an NSAID (ibuprofen, motrin, advil, naproxen) and if they bother your stomach you can think about adding a stomach protecting agent (proton pump inhibitors like prilosec) or switch to a COX-2 inhibitor like Celebrex.


Fifth: When the fourth step doesn’t work for you, it is reasonable to ask about going to opiod analgesics (mixed with Tylenol or not).


Sixth: Other slow acting drugs for osteoarthritis are also reasonable to try: Glucosamine, chondroitin, hyaluronic acid, diacerein do appear to provide some symptomatic relief with low toxicity.


Seventh: Injections of steroid or hyaluronate acid into the joint can be considered for a flare that is unresponsive to NSAIDS and pain medications.


Eighth: Surgery. If you are young a joint-preserving surgery may be attempted but for most joint replacement has to be considered in patients with radiographic evidence of Osteoarthritis who have refractory pain and disability.


What has your experience been?


Dr O.


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Displaying comments 14-1 of 14
14
Hi, I am a 40 y/o mother of 4, i have severe grade 3 & 4 osteoarthritis in both knees, I had a doulel knee arthroscopy in march 08, where the doctor trimmed meniscies and filed back some arthritis on the back of my knee caps.. Have been worse since the surgery. My knees constantly ache, and the ache worsens during the course of the day, I take paracetamol or ibroprofen during the daytime, but it doesnt do too much. i take trammadol 100mg at night to help dull the pain to alllow me to sleep.. I have tried swimming, but it still hurts, i cant lose weight because i cant move much... am at wits end... i am afraid to have the cortisone injections, as they are extremely painful. I also have plantar fasciitis which drives me just a s crazy.... Should i opt for the knee replcements..... and will it reduce or remove the constant aching???
By AUSSIEJOJO  Jan 30, 2009
13
My husband & I recently joined Snap Fitness which just opened up in our neighborhood. We have been working out 5-6 days for the past 2-3 weeks and we have really noticed an improvement with our minor knee pain/stiffness. The ARC (elipical) trainer has really helped my left knee which had been gradually talking to me more for the past few months. I don't have nearly as much problems with it now. I am expecting it to gradually get better as I get more in shape and strengthen the muscles which had gone to flab. I recommend everyone to join a nearby gym fitness center to get in better shape. A deconditioned body really has a lot of bodily querks which when getting reconditioned through exercising will decrease and eliminate those bodily querks.
By graciejoy  Jan 26, 2009
12
Am well overdue - side effects confine me to script only painkillers (have RA as well). Afraid of falling, as I live alone - neighbour scraped me off garden pavers 3 years ago: I tripped up: seen specialist - he ordered MRI - have not had it done, as gum disease & a jaw malformation which requires surgery (there's only 1 f-max. in the State) are preoccupying me. I keep self below 50kg. deliberately - cannot take NSAIDS - stomach ulcer aged 31. JaneD.
By JaneD  Jan 26, 2009
11
Dear Dr. Orrange,

Thank your for this information. I know that osteoarthritis is also a wide-spread disease here in Europe. I have it since many years, combined with fibromyalgia and CFS. The fact that I also have a metabolism problem through which I gained double the weight of before did not make it easier for my joints. For 8 years I was on disability pension. But then I found the Magnetic Field Therapy, which is widely used by physicians all over Europe. Using the MFT keeps me pain-free for many years now. I know that there are several models available on the market. The best I have found was developed by a team of over 30 scientists of 2 European universities. But I know there are also MFT systems available in North America. I hope this would help some of your patients as well.
By Healthfreedom  Jan 25, 2009
10
I have tried all of the above. Synovous shots, steroids, anti inflamatories (duclofenac sodium) and nothing works. The dcotors say I am too young for knee replacement(44). My quality of life is deminished. I so want kne replacment surgry to get my active life style back.
By PeachesInGa  Jan 24, 2009
9
Dr O, There is a product available that assists the body in repairing the damage. A friend used it and she did not have to have a replacement. She is completely painfree. It is something that stimulates the body to produce it's own adult stem cells. It is extremely effective for all kinds of health problems. It has no side effects except for total all over health and the slowing of the aging process ( my husnband is growing hair all over his bald spot.) Please contact me jordaan1@mweb.co.za for the info as the FDA rules restricts us from promoting health products through testimonies. By the way my son used it and both positve and negative symptoms of his Schizophrenia is gone.Martietjie
By martietjie  Jan 24, 2009
8
Hi, I cant relate to knee replacement yet, but am the recipient of two hip replacements, the later one being in November 2008, done after many many years of disability, pain and stress. I did start off with exercises including hydrotherapy, physiotherapy etc., then creams, pills etc. etc. but since having the op, my whole world has opened up. I am gradually now getting the confidence to do things that I haven't been able to do for many years, for example bend down to pick something up, have good sex, get out of the car normally in a normal parking space. It is definitely worth perservering for the op. I am 52 years old which is youngish for these ops, but hip problems started when I was 13. Good luck to all those sufferers out there, remember, keep on moving - it is all worth it in the end....... Sandy
By sandygal  Jan 23, 2009
7
Tylenol helps me (flexeril at night) . Is Pulse Signal Therapy effective? Just stumbled on it and it's used more on horses and dogs than humans, but I'm curious about anything that's non- surgical/invasive.
By FeelingRough  Jan 23, 2009
6
One food product that seems to make arthritis so much worse is soft drinks, Pepsi specifically. It seems that the ingredient that gives soft drinks the fizz when you pop open the can (phosphorous, I think) actually aggravates joints and causing irritation. My father drank diet Pepsi to the day he died and he was in horrific pain for the last 5 years of his life. I have had this same problem, only I was able to make the causal link to this product. When I stopped drinking soft drinks, the pain went away. Check your diet and get rid of these kinds of products. It has been really hard to give up Pepsi for me, as I love the drink, especially on a hot summer day. Once in awhile, it can be consumed without problem. Just not every day and not can after can.
By Cybercatxq  Jan 23, 2009
5
Dr. Orange,
I personally have used the Voltaren cream. It works very well. I cannot take the oral forms due to Gerd.
Joan
By jg07  Jan 22, 2009
4
Thanks, this information was very useful since my mother suffers from a reoccuring knee pain
By marcuspete  Jan 22, 2009
3
I second xta's comments. Detecting and eliminating foods that contribute to a chronic inflammatory state can be pivotal in reducing osteoarthritis pain. I have seen it countless times with my clients.

Bonnie Minsky MA, MPH, LDN, CNS
By nutrocon  Jan 22, 2009
2
When I was 39, I started experiencing symptoms of OA in my fingers, ankles and feet. I could barely walk upon rising from bed in the morning! At the same time, my 5-month infant started showing symptoms of eczema. Because a naturopathic doctor recommended a gluten free-casein free diet for my infant, suspecting his eczema was exacerbated by food allergies, and because I was breast-feeding, I cut products with wheat-gluten and dairy immediately out of my own diet. I'm not exaggerating in the least when I say that within two weeks, all of my joint pain DISAPPEARED, and it has not returned since. My infant son also has been spared from severe eczema outbreaks as a result of our dietary habits. We have been gluten-free and casein-free for almost three years now, and I'm convinced this diet has safe-guarded our health. I'm now a regular jogger and can run three miles easily, without pain. My son's eczema remains mild and confined mostly to his hands.

Melissa Diane Smith's book Against the Grain was an informative and enjoyable read to help me understand the negative effects of wheat gluten on the human body.

I hope my comments help others.
By xta  Jan 22, 2009
1
My arthritis was never helped or eased by any of the drugs prescribed, and believe me, this is one of the most commonly over-prescribed conditions out there.

What actually helped me the most, ironically, was walking. At first, I started slow walking in the water at the community pool. Then I did a fast walking-in-water routine, a strenuous workout that helped trim my hips. This was an added bonus!

Then, I started a leisurely pace of walking around the block, a walk block at a time. I seldom experience pain in my knees or hips any more. If I spend a few hours sitting in the same position, as when I'm knitting or on the computer, my knees and hips start to feel achy. That's when I put a leash on the dog and go for a walk to the park.

Exercise has really been the most beneficial thing to do for my arthritic joints and getting that fresh air is so much nicer when you know you have a hot bath waiting to come home to afterward.Ahhh!
By Cybercatxq  Jan 22, 2009
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