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Discussion:
Some Foods Block the Effects of Meds
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In conjuction with 15 things not to say to an RA patient... I found this article on arthritis today.

http://www.arthritistoday.org/treat...
Posted on 03/01/11, 04:49 pm
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Reply #1 - 03/01/11  4:51pm
" urgh I hit submit before I was ready LOL I find the alchol one a riot. Seriously with all the meds we take to keep us kicking someone would add alchol to the mix? Even if I think about having a wine cooler in the summer my husband injects my thoughts before I even open my mouth! He works as a Validation Engineer at Cehpalon. So he knows his stuff.

Be Aware: Some foods and beverages can block your meds.
By Camille Noe Pagán

If you’re like most people, you down your pills with juice or food, thinking you’re doing your stomach a favor by not taking the medications alone. As it turns out, you may be doing more harm than good due to food-drug interactions.

Recent research shows that foods and beverages can have a dramatic effect on how the body absorbs certain medications.

“Twenty years ago, a team of researchers and I realized that grapefruit juice could cause many medications to be as much as 10 times more powerful than they’re meant to be,” says David G. Bailey, PhD, clinical professor of pharma­col­ogy at the University of Western Ontario in Canada.

Thanks to their research, more than 50 medications now carry cautions about grapefruit juice on their labels.

Now Bailey has discovered that grape­fruit, apple and orange juices can actually have the opposite effect on some other drugs. “They block the pills’ absorption, so you get less or even no benefit from taking them,” says Bailey. “This might cause someone to think that they need to switch to a ‘better’ medication – when in fact changing what they eat, or when, would make the drug effective.”

Here are five common pill blockers to watch out for:

FOOD: Milk and yogurt
BLOCKS: Iron supplements; many antibiotics, including fluoroqui­no­lone, cipro flo­xacin and “cycline” anti­biotics like tetracycline; thyroid hormone; and penicillamine (Cupri­mine, Depen), a disease-modifying anti­rheumatic drug

FOOD: Apple, orange and grapefruit juice
BLOCKS: Disease modifying anti-rheumatic drugs, including metho­trexate (Theu­ma­trex, Trexall); cyclo­spor­ine (Gengraf, Neoral, San­dim­mune), a drug used for severe psoriasis and rheumatoid arth­ritis; beta blockers like acebutol (Sectral); cancer drugs like etoposide (Eto­pophos, Vepesid); alendronate (Fosamax), an osteoporosis drug; the allergy medicine fexofenadine (Allegra); some antibiotics including ciprofloxine (Cipro) and levoflox­acin (Levaquin)

FOOD: Coffee
BLOCKS: Alendronate; the antibiotic penicillin

FOOD: Foods rich in vitamin K, including leafy green vegetables and liver
BLOCKS: Blood thinners like warfarin (Coumadin)

FOOD: Alcohol
BLOCKS: Anti­depres­sants, especially mono­amine oxi­dase inhib­itors (MAOIs) like tran­yl­cypromine (Par­nate) – although people taking SSRIs like fluoxetine (Prozac) should avoid drinking more than moderate amounts of alcohol as well, as it counteracts their benefits.

How long should you wait?

In most cases, you can consume a potentially pill-blocking food or beverage about three to four hours after you’ve taken your meds, but it’s best to ask your pharmacist, who can tell you for sure. Plus, she can check to see if other medications or supplements you take might further affect how your body absorbs your medicines "
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Reply #2 - 03/01/11  7:40pm
" thanks for posting this!

...about mixing alcohol and drugs, i no longer take mtx, but i did drink 1 - 4 drinks per week on that med, with my rheumy's knowledge, if not full blessing. i'm now taking warfarin for DVT/PE and drink about the same amount as long as my INR range is on the low side. "
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Reply #3 - 03/02/11  1:02am
" thanks for the info,
I knew food and such can do this, but not knowing which one does what. It's nice to have a list "
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Reply #4 - 03/02/11  6:17am
" HMMMM I always take all my meds with my morning orange juice. That includes arava, prednisone, amd my weekly methotrexate as well as my BP pill. Not quite sure how to get around this because I love the morning juice but ...I wonder about switching all my meds till evening? I really try to keep fruits in my daily diet! "
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Reply #5 - 03/02/11  10:20am
" Thank you for doing the research for us! Apple juice, too?! It seems so benign. Guess I'll be taking everything with water. "
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Reply #6 - 03/02/11  11:05am
" I alot of times take my pills with oj and take mtx shots so since it isn't a pill, wonder if that's ok. I'm hitting my anger mood - haven't accepted this yet. "

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