What is Myasthenia Gravis

Myasthenia gravis (MG) is a neuromuscular disease leading to fluctuating muscle weakness and fatiguability. At about 14 cases per 100,000 (in the U.S.), it is one of the lesser kno...

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Discussion:
Mestinon
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Has anyone seen a difference in the effectiveness between Mestinon and the generic version? I am taking the generic and have not seen any improvement.
I am 63 and have been diagnosed with mg for a year now. My only symptom is a droopy eye. I have gone as high as 390mg per day.
Posted on 11/15/07, 10:11 am
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Reply #1 - 11/15/07  1:11pm
" Medications work differently for everyone. So you may, indeed, not have results with the generic. I have had positive results. But I also take Prednisone. That's why we think it started working so quickly. Hope you can figure it out and get on something that will help you.
Becky "
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Reply #2 - 11/17/07  7:25pm
" One neurologist that I saw who
was a MG specialist said that
the regular Mestinon is stronger than the generic. I
am fine on the generic because
I am very sensitive to it.
Maybe the regular would help
you more. Good luck! "
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Reply #3 - 11/17/07  11:46pm
" i have taken both and for me the generic seems to give relief with fewer side effects when on the regular stuff my side effects were horrible. I take 120mg of the generic every 3-4 hours plus 40 mg of prednisone. i think it depends on the person.. "
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Reply #4 - 11/19/07  4:04pm
" I have been on the generic version of Mestinon since July. I had many symptoms starting with droopy eyes,facial symptoms,and weakness of extremities. I also,went up to 390mg a day and that is when the symptoms subsided.I still have the right eye remains droopy especially when I am tired. I am 61 years old. Fran "
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Reply #5 - 01/16/09  11:36am
" The MG Association here in Kansas sent an alert to all of us about a brand called Glbal. I was getting this brand and found my pills were crumbling almost immediatley after the bottle was exposed to air. I took the alert to my drug store and they immediately stopped stocking this brand. I have to take the generic mestinon for my 60mg every two hours dosage but take the Mestinon for time release. I also get Mestinon in the liquid form which seems to work faster and is more potent than the pill. I do have to be careful with the liquid as it interfers with my breathing unless taken in small sips. "
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Reply #6 - 01/16/09  5:56pm
" ok I dont know if this helps or not but in general, generic drugs are required to have the exact same chemical makeup. So, generic or name brand it should be the same stuff, only difference is the price. I take pyridostigmine, generic for mestinon and it works great for me. It only lasts about 4 hrs tho and from the research I have done it is difficult to get the right dose because too much and not enuf can cause weakness and the symptoms to become worse or no difference at all. I dont have the droopy eye nemore, but the double vision actually got worse for awhile after starting mestinon. I have weakness in my arms and legs for the most part, and fingers, etc. hope this helps "
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Reply #7 - 01/17/09  10:23am
" I recently switched over to the name brand and there is quite a difference. I do pay a higher copay it's worth it. "
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Reply #8 - 01/18/09  9:50am
" My husband is on the brand. When he took the generic he actually ended up in the hospital in
crisis. He recently went thru crisis and now it seems the Mestinon may be causing some of his side effects. Such as a dry cough. Does anyone know how to combat this cough? He is also on prednisone 20mg every other day. "
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Reply #9 - 01/23/09  5:01pm
" I take the generic mestinon and it works for me. I also take prednisone 20mg daily and cellcept. I also,started with the ocular symptoms. It seems like the prednisone is what really works for the ocular symptoms that I have. I am 62 I was diagnosed March 07 Fran. "
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Reply #10 - 02/07/09  7:30pm
" Hi I just found out I have MG. The doctor did the repetitive test. He said I could just not give you any treatment or medicines. Has anyone ever not taken meds for this and been alright? He did give me pyridotigmine br 60 mg 2 times a day. He said that one blood test came back ok but he was waiting on another one that could take a month. I just can't figure out what he is talking about, can any of you? "

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