What is Multiple Sclerosis MS

Multiple sclerosis (MS) is a chronic disease which affects the brain and spinal cord. MS can cause a variety of symptoms, including changes in sensation, visual problems, muscle we...

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Discussion:
aspirin, fatigue, vascular insufficiency
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Before I was diagnosed with MS, I noticed that whenever I took aspirin, whatever fatigue I was experiencing, went away. Since I have been diagnosed, it still works! I did some internet searches and found out that a study has actually been done on this regarding the use of aspirin in treating MS fatigue and the study concluded that it does relieve MS fatigue ! I don't know if the patients were on the DMD's during the study but I am not and it does work for me. I take the dispersible kind so I don't have tablets sitting in my stomach which can be hard on the stomach lining. I take the equivalent of three tablets and only when I get VERY fatigued which is not very often. Some of you may be on meds that would prohibit aspirin use but for those of you who are not, you might try it! Works for me!

The idea actually fits in with the paper Sherryalton posted under the heading CCVI concerning a theory regarding the connection of vascular insufficiency and MS. Aspirin is a blood thinner which would improve vascular circulation. In fact, there is a condition called Hughes Syndrome which has many of the same symptoms that MS has. It is also known as "sticky blood" and is treated with blood thinners from aspirin to warfarin depending on severity. Here is a link regarding the aspirin study http://www.msneighborhood.com/cont...

and here is a link regarding Hughes Syndrome http://www.hughes-syndrome.org/ .
Posted on 10/27/09, 08:10 am
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Reply #1 - 10/27/09  10:37am
" thx caroline "
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Reply #2 - 10/27/09  2:48pm
" Caroline, you rock!! That makes since and I am going to the web site right now to check it out. Also, sherry, you rock too by keeping us informed with such good info!!!

Caroline, exactly what kind of asprin is it that you are taking that doesn't just sit in your stomach? "
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Reply #3 - 10/27/09  3:01pm
" Oh, how many mg. do you take? I just looked at the article and it talked about a baby asprin, which a doctor recommended that I take years ago...to help prevent heart attack and stroke. "
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Reply #4 - 10/27/09  5:35pm
" Well, I used to take the tablets until someone told me about the dispersible kind that you put in water. You might be able to find this in the drug stores in the States or at WalMart. If not, you can order them from Amazon. The two brands I know of are BC Powders and Goody's Headache Powders. I take about 975mg at a time. I could probably take more but this works for me.

Some interesting info along these lines from the Bayer Aspirin site-

How does aspirin work?

Aspirin reduces the production of hormone-like substances called prostaglandins, which are produced in tissues throughout the body. Prostaglandins have many functions. They are part of the chemical messenger systems involved in feeling pain, fever, the redness and swelling that can accompany injuries, and even in contracting certain muscles, for example, the uterus. Since aspirin lowers the amount of prostaglandins, it can help alleviate conditions like pain, fever and the discomfort of menstrual cramps.

Aspirin also reduces production of substances involved in the early stages of our body's blood clotting mechanism. This is why doctors may prescribe aspirin, as part of a regimen, for appropriate individuals to reduce the risk of cardiovascular events, such as heart attack or stroke.

Now, when I read the first paragraph of that, the word prostaglandin jumped out at me. I had come across that word in doing some reading on MS. This from a neurology abstract-
(it wouldn't let me copy and paste the article so here is the link)
http://www3.interscience.wiley.com...

So if there has been shown to be a link of high prostaglandins in MS patients which causes the inflamation and aspirin reduces the production of prostaglandins, it seems that aspirin would be very beneficial to MS patients! Plus it thins the blood so that the blood flows more smoothly! Interesting!

Whatever the mechanism by which all this works, I do know that it "cures" me of the fatigue and brain fog I experience on occasion. "
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Reply #5 - 10/27/09  11:31pm
" I have been having such a problem with my feet, right one now. It hurts to walk and I am packing to move and we are house hunting. Not a time for hurting feet. So, you take the 975mg at a time. How many do you usually take, or is recommended? I use to take the baby asprin and chew it up. I don't like the taste of BC Powder, but if it would help relieve the inflammation in my feet, I would drink monkey pee! LOL

I am going to Walmart tomorrow to get som Vit. D-3 and will also get asprin or BC. I need some fatigue relief and I am tired of aching feet when I have to get this house packed up. House hunting started today, so I will have to have my feet in shape to go house shopping.

Thanks to you and sherry for the good info. I can't say enough how much this site has and continues to help me!!!

Blessing to everyone!! "
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Reply #6 - 10/28/09  8:54am
" When I do not have the powder variety, I take 3-325mg tablets. Of course I take this with food as taking tablet aspirin on an empty stomach can be harsh on your stomach lining. Some aspirin is coated which would help against this. Taking the powder in water works very quickly and is not hard on your stomach. If you can't find the powder, you could crush UNCOATED tablets but they are hard to find. Let me know if this works for you too regarding the fatigue and foggy brain. "
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Reply #7 - 10/28/09  11:28am
" Really, thanks. I have been unable to take aspirin, but will make another try at it. I had noticed that when I have severe fatigue, stiff muscles and cramps, that there is a feeling of heat or fever involved. Great idea. "
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Reply #8 - 10/28/09  2:54pm
" Yes, the aspirin does seem to work. I personally think that when you are achy and sore it exhausts us. I had someone tell me that after being in severe pain so long your mind shuts it out and deals with it. Then when it gets totally out of control we notice it. I realized that I do shut a lot of the pain out...

I have some questions. I hope someone can help me with. I am not sure if I have MS. I am being sent to another neuologist. I has 2 in the hospital not sure of my condition. I now am totaly unstable on my feet. I use a walker. I have had the numbness in toes for about 2 years. Now I have the tingling and pain in my arms, legs and center of my face around my nose then flaring out. I have the exhaustion...

Now I HAD a period of several years of my short term memory going. (Actually it was almost totally gone)(I had to write everything down) I did not get that back until this summer... is that what they call the brain fog? I could not remember anything for no body...LOL!for almost 10 years.

I am to be sent to therapy when my medicaid is okayed...I feel myself failing and want to get stronger. What type of exercises do I do to help. Is there a place online I can go. I have not worked for a while and spending any money is out of the questions...I have none right now.

I am filing for disability...My family and friends don't want me to think I have MS. They feel my life will be cut short.

Please can someone help me with advise. I feel I can face and beat this, I just need some positive input from others than just ignoring the fact that physically I have been falling for 6 years and now it may have a name and I will know what to do to get stronger.

Thanks for the help anyone can give me. I know that with the right input anything can be beat. I plan to beat MS if that is what I definitely have. "
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Reply #9 - 10/28/09  5:24pm
" Hi Caroline, I take the soluble aspirin also, i think it does help me. However i also have to take Zantac tablets to protect my stomach. "
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Reply #10 - 11/06/09  8:25pm
" Am going 2 try it!!!!!THANKS,,,,,,,,,,,,,,,,,, "

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