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Discussion:
Avonex Users - Take Note
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On February 28, 2012 Biogen Idec announced that the United States Food and Drug Administration (FDA) had approved both a new device (the Avonex Pen) as well as a new initial-dosing regimen for Avonex (interferon beta-1a). These two approvals are aimed at assisting patients who are either taking Avonex presently, or who are just starting Avonex.
Posted on 04/17/12, 11:03 am
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Reminder: This is a support group for Multiple Sclerosis (MS). We trust you will do your best to remain positive and helpful. For more information, see our rules of the road.

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Reply #1 - 04/17/12  11:04am
" sorry, I forgot one of my important parts of the post!

The Avonex Pen
The Avonex Pen is the first intramuscular autoinjector approved for an MS medication. The other self-injected treatments for MS are given via subcutaneous injections, which do not require as deep of an injection. Since Avonex is injected intramuscularly, patients may find this type of self-injection to be more difficult, and they may experience increased pain and anxiety as well. The Avonex Pen is designed to be easier to use (than the present Avonex Prefilled Syringe alone) and is designed to reduce both pain and anxiety.

The Avonex Pen incorporates the current Avonex Prefilled Syringe, along with a thinner and shorter needle. Other features of the Avonex Pen include an automated insertion of the needle and delivery of the medication, as well as a design that helps to stabilize the device while performing an injection.

Initial Dosing Regimen
The FDA has also approved a schedule for starting low and gradually increasing the dose of Avonex at the start of therapy. The reason for this change in the initial dosing of Avonex, which introduces the drug gradually (known as titration), is to help reduce the incidence and severity of flu-like symptoms. These can often occur when starting an interferon therapy.

The new dosing regimen is provided on the Avonex label to physicians and patients, and may be facilitated using the Avostartgrip kit. This kit includes a set of three devices that work with the Avonex Prefilled Syringes, each filled with the titrated doses of Avonex. Specifically, 7.5 mcg is given in the first week, 15 mcg is given for week two, and 22.5 mcg is administered for week three. The full dose (of 30 mcg) starts in week four. PLEASE NOTE: This titration schedule should only be used by individuals who are just starting Avonex.

For More Information
For more information, please see Biogen Idec's press releases on these topics at www.biogenidec.com. For general information about Avonex, please visit avonex.com." title="http://www.avonex.com." target="_blank">www.avonex.com. "
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Reply #2 - 04/17/12  12:26pm
" Thanks for sharing this information. I have heard something about the Avonex Pen. I am able to do my on injections now. It only took me a year. I wonder if the pen will be better than the prefilled syringe. "
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Reply #3 - 04/17/12  3:26pm
" Thanks,I was all excited when you posted the other about the pen, now I realize all the problems people here on subcutaneous shots have, now I'm re thinking this new way, avonex doesn't hurt and no skin problems besides an occasional itch on day one. I want avonex on a pill!!!!!! LOL

Thanks, Alma "
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Reply #4 - 04/19/12  7:58am
" this avenex- is it better to take than copaxone- lol- should of looked it up- ha- not thinkin!!! hugs!!! "

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