Using DHE actually isn't new and was used as early as 1943. Apparently being hospitalized and using it that way is new. Also, it can cause a rebound migraine. Read the links carefully to give you even more info.

I remember trying the drug Migranal (which is actually DHE and I didn't realize that until I read the article below right now) and it didn't work for me because I did not have the type of migraine that it works for. Check the link below for more info:

http://headacheandmigrainenews.com/dhe-migraine-treatment

Thanks for the great info, AsTimeGoesBy. I read that the treatment had been around forever but the serious side effects are definitely a concern. I have weird reactions to drugs anyway so I think I'll skip one that is injected and then can cause rebound headaches anyway.

It seems to work for some, but like everything we try in hopes of a cure, individual results may vary.

Lynn, I'm just sorry you're suffering from migraines and we're all in the same boat. I hope that whatever you decide goes well and you let us know. That helps the rest of us here.

You helped me because I learned that what I had taken was DHE. That was new to me!!

Sure, I'd be happy to share any treatments that work. It's great that we have this forum and we can all help each other.

My neuro just took me off Namenda (Alzheimer's medication) because off label it's supposed to help. I'm finally coming out of my spaciness and dizziness, although it did help with sleep and depression. Namenda might work for some others as it has very few serious side effects and doesn't seem to interact with other meds.

She now has me taking a Amerge (a triptan) twice a day for 2 weeks to get me off my once a day narcotic painkiller. Gee, can we say Rebound Headache?

But I won't be trying out the DHE anytime soon!

I'm currently 3 days into a 10 day, twice a day regime of the Migranal nasal spray, and it's working great. It just makes my nose stuffy, but I'm fighting a cold, anyway. I'm on it for rebounds from triptans and Tylenol. Along with it I'm on the following;

Indomethacin 50mg;
4x day for 5 days

Baclofen 10mg: added to Indomethacin or Anaprox, up to 3x day as needed.

I've had 24/7 headaches for approx. 4 years now with no explanation. They started out gradually and didn't develop into rebounds until the last year when I had my cervical spine replaced. That had the opposite effect of what they intended and I went overnight from having 1-2 migraines per week to 3 per day with no explanation as to why. I've been working with an expert headache Neurologist since the surgery and we've finally made a breakthrough, after two full Botox treatments, steroid injections and bursts, etc. I've also had cervical nerve injections and blocks by a spinal pain specialist since my surgery in January that did not touch my headaches/migraines.

Hi Melli: I am so sorry for what you are going through. I went through migraines every day for a year and nothing stopped them. I thought I would go out of my mind. And I ended up in the hospital E.R. Then I was sent to the neurologist in my plan that deals with migraines and with the occipital neural blocks, he gave me a lot of relief for a few years. Then I became allergic to the lidocaine used in them. Then we moved to botox and that helps a lot. I still have to use the preventative generic Topamax, but the botox works.

My biggest fear is that eventually the botox won't work or that I will become allergic and then I'm back to having migraines 24/7.

Please let us know how treatment works and new things you try. Because what works for you may be new to someone else and be the miracle that helps them. I so hope that you will find relief from migraines.