Lupus Support Group

I guess I should have Said class...



The World Health Organization has divided lupus nephritis into five classes based on the biopsy.

Class I is minimal mesangial glomerulonephritis which is histologically normal on light microscopy but with mesangial deposits on electron microscopy.

Class II is based on a finding of mesangial proliferative lupus nephritis. This form typically responds completely to treatment with corticosteroids.

Class III is focal proliferative nephritis and often successfully responds to treatment with high doses of corticosteroids.

Class IV is diffuse proliferative nephritis. This form is mainly treated with corticosteroids and immunosuppressant drugs.

Class V is membranous nephritis and is characterized by extreme edema and protein loss.

Class VI Glomerulosclerosis


I have active focal proliferative nephritis and some of my kidneys have inactive membranous nephritis..but for now my kidney function isn't too terribly bad so im lucky there.. my lupus is agressive and we're going to try to nip this in the bud..My kidney doctor did say that if i was a class IV she would have admitted me for cyclophosphamide..so i got lucky there.. my protein is at 300+ and moderate ammounts of blood with a urine culture negative for bacteria.

I am doing better now that i better understand things.. cellcept is an organ rejection med since Us lupus patients have overactive immune systems and attack our own bodies im hoping this treatment works for me..