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Discussion:
I have IGA deficiency and a sinus infection?
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Well I am posting here to see if anyone else has gone through this. I have had a sinus infection for about 6 months, maybe longer, I have tried all antibiotics and nothing works. Been to a doctor, then a ENT, then a infectious disease specialist. The disease specialist found out that I had iGA difficiency, and my regular doctor says because of the IGA deficiency the medicine will not work until the levels get higher or back to normal. I was wondering is that right? I have an appointment with a doctor to help treat the IGA deficiency, but honestly im losing all hope that this infection wont ever go away, and I graduate college in two weeks, and its going to be hard finding a job when im sweating from a fever.

symptoms
-fever(although its not high, i start to sweat and such)
-One side of my nose is always blocked


So was wondering if anyone went through anything like this, and any tips or suggestions I should do, or tests to have done to get rid of this infection. Thanks
Posted on 04/24/11, 07:43 pm
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Reply #1 - 04/25/11  8:48am
" You stated "my regular doctor says because of the IGA deficiency the medicine will not work until the levels get higher or back to normal". IGA deficiency is not treatable, so you're levels WON'T get back to normal. Have you been tested for CVID? It's quite common in people who are IgA deficient. I would recommend finding a doctor who specializes in treating people with a Primary Immune Deficiency - contact www.primaryimmune.org and get a list of doctors in your area. I have CVID as well as am IgA deficient and antibiotics work on me. Sometimes they have to use two antibiotics at once and I have had to have sinus surgery in the past but the infections DO go away. Hang in there. "
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Reply #2 - 05/01/11  8:42am
" Your doc is not right. There is no know way to increase IgA; no know treatment. We can treat IgG deficiency, but not IgA.

It sure sounds like you have a sinus infection from what you describe.

Were I you, I'd find an ENT at a major / teaching hospital and tell him what is going on. Ask him to culture what is going on in your sinus. My bet is they just have used the wrong antibiotic, some sinus gunk is more selectable to certain antibiotics than others.

Have you tried an old fashion nedi pot to try and loosen up the gunk. It's cheep, a bit disgusting at first, can never hurt and might help. My ENT, chairman of the department at the Cleveland clinic, swears by them and it has been effective for me. Any drug store will have them. I like the plastic squeeze bottle the best. I'd try it for a few days while you are waiting for the ENT appointment

good luck, congrats on your graduation . . . and now the real world begins "
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Reply #3 - 05/01/11  8:49am
" By he way low IgA is reasonably common, most patients are without symptoms. You may get a few more infections and they will need to be treated aggressively with longer and stronger courses of antibiotics.
But you should be absolutely fine. You might want to follow this link. It will tell you a lot more about IGA deficiency. It is from the Immune Deficiency patient had book
www.primaryimmune.org/publications/... "
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Reply #4 - 05/01/11  12:53pm
" yes I use the neilmed sinus rinse everyday, along with a nasal spray, the one im on is currently a steroid kind? but that doesnt even help, im wondering if im going to need surgery to be able to breath out of my nose again, i hope not "
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Reply #5 - 05/03/11  8:48am
" i have chronic sinusitus and pretty much everymonth i get cultures done and like mark said get that done mine is resistent to alot of antibiotics so if your dr puts you on just any antibiotic its not gonna work.

mostly only one or two work for my infections. this last one only ONe antibiotic showed up sensitive to it and i was put on that

also i was recently put on a nasal nebulizer with an antibiotic as well. as the ent about that. "
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Reply #6 - 05/03/11  8:51am
" another trick of the trade i use to get some of the thick gook out.

put some saline on a piece of tissue or something and stick it up your nose, make sure its saturated with saline
leave it up there for a while after like 5 or ten minutes blow your nose.

when i do that i get a really thick piece of gook out of my nose an dit brings some relief. "
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Reply #7 - 05/28/11  6:07pm
" Sometimes sinus infections can be fungal, not bacterial. Antibiotics will actually make it worse! So it you are getting cultures done, I would ask if the can check for that as well. From what I understand, it is something that is becoming seen much mre often! "
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Reply #8 - 11/04/11  1:49pm
" It was just discovered that I am IgA deficient. I was told to see an immunologist. What kind of doctor did you see for you IgA deficiency? I am having trouble finding an immunologist. "
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Reply #9 - 11/04/11  10:27pm
" Immunologists typically fall under "allergy/immunology" "

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