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Discussion:
Lexapro vs Celexa
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I have been hearing a lot of good response to Lexapro. I have been on Celexa for a number of years and feel like it just doesn't work like it used to. (even off tx). Looking for opinions on both. Thanks
Posted on 11/05/09, 03:11 pm
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Reply #1 - 11/05/09  3:22pm
" Lexapro made my stomach ill. "
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Reply #2 - 11/08/09  12:51am
" I just switched from Lexapro to Celexa because I can get it for $4 at Wal Mart! It seems to be doing wonders for me! I actually wake up with a smile on my face these days, and sometimes even with a whistle in my tune!!!!!!!!!!!!!!! Everyone is different though, so you just have to see how it works for you. "
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Reply #3 - 11/08/09  1:06am
" Lexapro (Escitalopram) is the S-stereoisomer of Celexa (citalopram).

I take Lexapro in low dose on Tx and it works wonders for me in combo with another AD .

I know a number of people who have switched from the old drug to the new drug and have found it effective for the same reasons you mention "
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Reply #4 - 11/08/09  2:01am
" My hubby started Lexapro a few weeks ago. He has a long time history with depression and other issues. This is the first drug of many that has actually made him feel better. "
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Reply #5 - 11/08/09  6:13am
" No anti d is going to work forever. They can increase the dose, eventually sides emerge, or your body just gets used to it. Time to switch.
If you wake up happy to see the new day, its working for you.
Here, Lexapro runs around $80.month w/o insurance. Some drs get samples, don't be afraid to ask. "
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Reply #6 - 11/08/09  8:08am
" I love my Lexapro. I tried Celexa and it wasn't for me. "
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Reply #7 - 11/08/09  9:07am
" Ptriss, that is why I would like to try Lexapro, as I have been on citalppram for a number of years and don't think it is as effective as it used to be for me. Also Lexapro helps with the anxiety issues as well.

This is a good basic comparison of the two.

Comparing Lexapro to Celexa: An Overview
Lexapro® (escitalopram oxalate) and Celexa® (citalopram hydrobromide) are both prescription medications classified as selective serotonin reuptake inhibitors. They are very similar medications, although there are some important differences between the two.

Lexapro Versus Celexa -- The Chemical Differences
Lexapro and Celexa are very similar molecules.
Celexa was available first and is a mixture of R and S enantiomers of citalopram. Lexapro is just the S enantiomer of citalopram. Enantiomers are forms of molecules that are almost exactly the same but are "opposites." You might think of your right and left hands as being enantiomers. They are very similar to each other, but they are opposites (although they are mirror images of each other, if you put one hand on top of the other, they are different).

Depression research has shown that the S enantiomer of citalopram is much more active as an antidepressant than the R enantiomer, which is why Lexapro (just the S enantiomer) was developed.
Lexapro vs. Celexa -- The Practical Differences
Both Lexapro and Celexa are approved for the treatment of depression. However, only Lexapro is approved to treat anxiety. This does not mean that Celexa will not work for anxiety or that your healthcare provider cannot prescribe Celexa for anxiety; it just means that Celexa has not been adequately studied for anxiety treatment.

Another difference between Celexa and Lexapro is that Celexa is available as a generic, while Lexapro is not.

Regarding the effectiveness of the two medicines, some studies have suggested that Lexapro may be more effective than Celexa for depression treatment, while others have not found significant differences between these two medications.

Finally, many people find that Lexapro works for them when Celexa does not (or the other way around). If Lexapro works for you, this does not necessarily mean that Celexa will also work for you (and the opposite is true).

Lexapro vs. Celexa: A Summary
While Lexapro and Celexa are very similar chemically, there are a few important differences. Lexapro and Celexa are not interchangeable, and they are not approved for all of the same uses. Be sure to ask your healthcare provider about any other questions you may have about the differences between Lexapro and Celexa. "

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