What is Dementia

Dementia is the progressive decline in cognitive function due to damage or disease in the brain beyond what might be expected from normal aging. Particularly affected areas may be ...

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Advice:
What meds to try next
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I meet with my Father's doctors a week from Monday. Need to find out if the effectiveness of Namenda is starting to come to an end.

They don't feel Aricept will help, they feel Namenda is stronger than Exelon (still digging into this) I hate to go to any type of sedating drugs as he will lose his freedom of mobility at the NH. He is a high risk for falls already, but we've kept them at bay.

Paranoia and congnitive issues on the rise again.

Does anyone have any suggestions on what to try next? Thank you for any ideas you can provide. Cathy
Posted on 11/09/08, 12:11 pm
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Reply #1 - 11/09/08  6:30pm
" Cathy, I am trying to do some research for you on this. I thought you said your Dad was on Namenda and something else but if not you may want to see if he could be. This is from the rxlist website:

"A fifth drug, memantine (Namenda), is also approved for use in the United States. Unlike other drugs for AD, which affect acetylcholine levels, memantine works by regulating the activity of a neurotransmitter called glutamate that plays a role in learning and memory. Glutamate activity is often disrupted in AD. Because this drug works differently from cholinesterase inhibitors, combining memantine with other AD drugs may be more effective than any single therapy. One controlled clinical trial found that patients receiving donepezil plus memantine had better cognition and other functions than patients receiving donepezil alone."

The other drugs they mention for dementia are: tacrine (Cognex), donepezil (Aricept), rivastigmine (Exelon), and galantamine (Reminyl).

I'm so sorry this is happening. I know you have already had the obvious checked. Any results on those issues yet? Please keep me updated. Here for you my dear friend. Really big hugs, Kim "
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Reply #2 - 11/10/08  9:58pm
" All I can add is that my mom is on both Namenda and Exelon...the combination is working ok, she is not getting better but I know it is slowing the progress. Thinking of you "
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Reply #3 - 11/16/08  9:50am
" My Dad who`s 90 and I am living withcomplains and does not comply with medicines. He stopped his Aricept by himself but his heart Dr. gave him Nemenda. He usually complains about all meds but it`s been 5 days and no complaints. At least unlike the patch he was putting on himself because he can be very stubborn this Namenda pill he keeps in the kitchen and its a starter kit, very clear for 4 weeks . I pray it helps him. Best of luck Kathy,How long did it at all last effectively Kathy?...I pray that they come up with somethinghelpful with your dad Kathy . The same issues are on the rise for my Dad Kathy.....Kontiki....I am looking into increasing his Zoloft. "

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