What is Deep Vein Thrombosis DVT

Deep-vein thrombosis, also known as deep-venous thrombosis or DVT, is the formation of a blood clot ("thrombus") in a deep vein. It commonly affects the leg veins, such as the femo...

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Discussion:
COUMADIN VS WARFARIN
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Hey everyone. Just thought I'd pass along this bit of info. I have been on Warfarin since Sept. 14, 2007. Recently, I went to my immunologist/allergist, who also was an internal medicine doctor but her background is in LAB/PHARMACEUTICALS. She was telling me that coumadin is one of those drugs that it pays to get the real brand coumadin instead of generic (warfarin). Apparently, the binders and/or whatever else goes into the generic form can affect your INR levels b/c the drug is not as "pure" as coumadin. So, I decided to switch from the warfarin and see what happened. Lo and behold, she was right. As soon as I switched to the brand name coumadin, my INR shot up through the roof (over 6.0) even though my dosage was the same as the warfarin dosage (5 mg daily). This doctor told me that getting on coumadin and staying on coumadin and not warfarin should help get the INR where it should be and stay that way. This should eliminate all the fluctuations on a weekly basis, assuming you don't vary your diet and eat the foods from the no-no list. I've kept my diet the same the whole time and switching to brand name was the only thing I changed, so there has to be some truth to this. Now my coumadin dosage is smaller and it seems to be working like it should. My hematologist (and even a vascular surgeon that I saw for a consultation) said there was no difference between the generic and brand name, but obviously the doctor with the lab background knew what she was talking about.
Posted on 02/06/08, 02:02 pm
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Reply #1 - 03/28/08  3:14pm
" INR management on coumadin is more stablized then the generic warfarin. I see a naval hospital for my INR management and the one time they put my on warfarin was like a roller coaster. I was getting my INR read ever couple of days. On coumadin I only go once a month. This is a well known problem amongst the medical community and the topic is discussed at medical symposiums.

Regards,
Tom in Connecticut "
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Reply #2 - 03/30/08  12:46pm
" I was on the coumadin for 2 yrs - the whole time i was in college. I was in my doctors office so much the nurse who drew my blood for testing of my inr level told me that she should just let me take my own blood myself. "
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Reply #3 - 03/31/08  9:03am
" Here is a little more info regardging Warfarin Vs. Coumadin:

http://www.fvleiden.org/ask/29.html "
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Reply #4 - 04/01/08  9:02pm
" I have tried both and it didn't make a difference for me.... "
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Reply #5 - 04/30/08  2:39am
" i've just recently switched from warfarin to jantoven...it's basically another brand name for warfarin. the downside to this is that the warfarin pretty much acted like a sleeping pill (it would knock me right out) while the jantoven seems to act like a caffine pill (it keeps me up). not sure if this is in my head or what...but i'm thinking about asking my dr. to just switch my rx back to warfarin. anyone else heard of anything like this? anyone else heard of jantoven? "
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Reply #6 - 08/19/08  2:02pm
" Jantoven is another member of the coumarin line of anticoagulants. Warfarin/Coumadin/Jantoven are all the same medication, just produced by different pharmaceutical companies. There shouldn't be any major difference in side affects exhibited. "
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Reply #7 - 08/21/08  6:00am
" My doctor said it doesn't really matter which one you take, as long as you don't go switching between brands. "
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Reply #8 - 08/23/08  12:34am
" I have been using warfarin for almost 5 years now and was getting it from barr labs , my INR was at about 2.0 most of the time. When I moved and transferred my script to another pharmacy, they gave me warfarin from Taro and I started to notice quite a bit of bruising and my INR had shot up to 2.8. Even though it is in the normal range, I had only been on that brand for a week at the same dose as the other brand. I brought this to the attention of the pharmacist who said it had nothing to do with it, but I disagreed. My dad was on warfarin 5 mg at home and when they put him in a nursing home for a short time on the same dose, except they used coumadin, his INR shot up to 4.3. It would be nice if they would treat it as the rat poison that it is! "
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Reply #9 - 09/03/08  8:48pm
" The NP I saw on Tuesday said the same thing as what JenniMc said. I can keep on generic Warfarin as long as I say with the same manufacture brand, in my case Barr I think is what they said I am taking. "

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