What is Celiac Disease

Celiac disease is an auto-immune disorder of the digestive system that occurs in genetically-predisposed individuals. It is characterised by damage or flattening to all or part of ...

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Advice:
Advice on anti tissue transglutaminase testing
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I have already done the IgE and IgG4 testing and was high positive for many things including gluten and dairy. My GP now is sending me for the anti-tissue trans testing. The problem is that I have been gluten free for a week...and he says I need to start eating it again for the test. He does not know for how long. Does anyone have any suggestions on how long I should gluten-load before going in for the bloodwork? (the sooner the better cus I'm sick from the stuff already and it's been less then 24 hours).
Posted on 07/03/09, 07:07 pm
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Advice:
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Reply #1 - 07/03/09  11:40pm
" I don't know about the blood test results. But i notice illness within the first 24 hour period of being glutened.

Of course, these are expensive tests so you might want to wait and see what others have to say on this issue.

Good luck to you. Come back if you are intollerant. Or stay and enjoy our company.
C "
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Reply #2 - 07/04/09  12:28am
" I think its highly unlikely that not eating gluten for a week will mess up your results if you go back to eating it for at least as long before your test.

When is your test scheduled?

Did you see any improvement in just one week? "
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Reply #3 - 07/05/09  12:39am
" I did see results with the diet within a week...not HUGE results, but I did feel a bit better. I had a lot of stomach cramping, but nothing like I get when I eat the things I'm allergic to.

I am Canadian, so my testing will be paid for by my medical. I also have the freedom to go whenever it suits me. I was thinking next Monday would probably be good...then I'm planning to do a fast before restarting my allergy-free diet again.

I have been feeling terrible since reintroducing the gluten. UGH "
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Reply #4 - 07/05/09  4:00pm
" A biopsy can give you a false negative whether you stop eating gluten or not. Most people dont have every square inch of their digestive tract affected at clinical levels. If you are unfortunate enough to have a piece of healthy tissue biopsied they can give you a false negative.

If you are feeling better on a GF diet, that is the most important test of all. You do have to control for placebo, but improvement is improvement. That is the only test that actually matters. "
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Reply #5 - 07/07/09  12:37pm
" Very true. I have decided to wait until Monday, then I will get the bloodwork done and start a fast before restarting my anti-allergy diet. I can't wait....I felt so much better when I was off of the gluten. "
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Reply #6 - 07/07/09  3:45pm
" although there may be a misprint, this may be something.

item 1.1.7 page 7 of the NICE discussion draft
http://www.nice.org.uk/nicemedia/p...

suggests that prior to blood tests, gluten should be be eaten in at least one meal each day for at least 6 weeks. "
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Reply #7 - 07/07/09  4:09pm
" when I said thee may be a misprint,
I was referring to the 6 weeks applying to
patients on a normal gluten diet;
I am wondering if they meant "not" on a normal diet.

if they really meant on a normal diet,
"not" on a normal diet may take longer . . .

some people may choose not to receive a medical diagnosis,
and some will try to get a medical diagnosis and get a false negative.

without a medical diagnosis it is important to consider other conditions
that may be causing whatever symptoms are present;
of course, people with a medical diagnosis may have them as well.

IMHO, it is important to get a diagnosis if possible. "
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Reply #8 - 07/09/09  3:36pm
" It is very important to get an accurate diagnosis, especially if you do not improve on a GF diet. If you improve totally after a few months on a GF diet, then whats the point of continuing to look for a diagnosis? If you do not improve, then you better figure out if its refractory Celiac or another condition entirely.

Just my personal opinion, but while it seems like 6 weeks is a reasonable time frame for someone who has been on a GF diet for a considerable amount of time, for someone who has only been on it for one week it might not be necessary to eat it for as long because the markers from the decades of eating gluten before that one week off have probably not gone away yet. "

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